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A+P O-Chem and Cell Review

Terms

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microvilli
minute extensions of the plasma membrane that increase surface area (usually for absorption)
rough ER
operates the cell's 'membrane factory'; creates integral proteins and phospholipids
hydrostatic pressure
movement of water and solutes through a semipermiable membrane from a region of higher hydrostatic pressure to lower hydrostatic pressure along a pressure gradient
examples of membrane proteins' functions
transport, enzymatic activity, receptors for signal transduction, intercellular joining, cell-cell recognition, attachment to cytoskeleton and ECM
filtration
the passive process that forces water and solutes through a membrane or capillary wall by fluid or hydrostatic pressure along a pressure (not concentration) gradient
example of filtration
movement of water, nutrients, and gases through a capillary wall; formation of kidney filtrate
examples of gap junctions
these junctions are often present in electrically excitable tissues, such as the heart and smooth muscle
simple diffusion
a passive process by which non-polar and lipid-soluble substances diffuse directly across the lipid bilayer.
nucleus
contains the 'genetic library'; dictates kinds and amounts of proteins to be synthesized
tight junction
a junction between plasma membranes of adjacent cells in which their integral protein molecules fuse together, forming an impermeable junction that encircles the cell
examples of desmosomes
for example, found in heart muscle and skin
example of simple diffusion
movement of fats, oxygen, carbon dioxide through the lipid portion of the bilayer
ribosome
site of protein synthesis in a cell; can be free-floating or membrane-bound on the Rough ER
hypotonic
eg, solutions that are more dilute (contain a lower concentration of non-penetrating solutes) than cells
osmotic pressure
a measure of the tendency of water to move into a concentrated solution
desmosome
"binding bodies" relying on intermediate filaments and cadherins that functionally "rivet" cells together in various locations across their membranes, and provide internal support within the cells
example of osmosis
movement of water into and out of cells directly through the lipid phase of the membrane via aquaporins
cofactor
the non-protein portion of a holoenzyme
gap junction
a communicating junction between adjacent cells, formed by hollow cyllinders composed of transmembrane proteins
mitochondria
the cell's 'power plant' provides most of the ATP supply
cillia
move substances in one direction across cell membrane
apoenzyme
the protein portion of a holoenzyme
smooth ER
performs lipid metabolism, synthesis of steroid-based hormones, detoxification (eg liver and kidneys)
example of facilitated diffusion
movement of glucose and some ions into cells
lysosome
the cell's 'demolition crew'; digests bacteria, viruses, toxins; degrades worn out organelles
channels
transmembrane proteins that serve to selectively transport specific substances, usually ions or water, through aqueous channels
example of tight junctions
junctions between epithelial cells lining the digestive tract, keeping digestive enzymes and microorganisms in the intestine from seeping into the bloodstream
facilitated diffusion
a passive process by which molecules such as glucose and other sugars, amino acids and ions are 'ferried' through the bilayer via through carrier proteins or through water-filled channel proteins
aquaporin
transmembrane protein that constitute a water-specific channel through which water can move freely and reversibly
examples of microvilli
often found in absorptive cells such as intestinal and kidney tubule cells
osmolarity
total concentration of all particles in a solution
cytoskeleton
machinery for locomotion/ motility
holoenzyme
an enzyme that consists of an apoenzyme and a cofactor

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