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Chabner LOM Chapter Sixteen

Terms

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albino
Person with skin deficient in pigment (melanin)
apocrine sweat gland
One of the large dermal exocrine glands located in the axilla and genital areas. It secretes sweat that, in action with bacteria, is responsible for human body odor.
basal layer
The deepest regions of the epidermis; it gives rise to all the epidermal cells.
collagen
Structural protein found in the skin and connective tissue
cuticle
Band of epidermis at the base and sides of the nail plate
dermis
Middle layer of the skin; also called corium
edidermis this word should be spelled
epidermis
Outermost layer of the skin
epithelium
Layer of skin cells forming the outer and inner surfaces of the body
hair follicle
Sac within which each hair grows
integumentary system
The skin and its accessory structures such as hair and nails
keratin
Hard protein material found in the epidermis, hair, and nails. Keratin means horn and is commonly found in the horns of animals.
lipocyte
A fat cell
lunula
The half-moon-shaped, white area at the base of a nail
melanin
Major pigment that gives the skin color. It is formed by melanocytes in the epidermis.
paronychium
Soft tissue surrounding the nail border
pore
Tiny opening on the surface of the skin
sebaceous gland
Oil-secreting gland in the dermis that is associated with hair follicles
sebum
Oily-substance secreted by sebaceous glands
squamous epithelium
Flat, scale-like cells composing the epidermis
stratified
Arranged in layers
stratum (plural: strata)
A layer (of cells)
stratum corneum
The outermost layer of the epidermis, which consists of flattened, keratinized (horny) cells
subcutaneous tissue
The innermost layer of the skin, containing fat tissue.
adip/o
fat (also lip/o and steat/o)
albin/o
white
caus/o
burn, burning
cauter/o
heat, burn
cutane/o
skin (also derm)
diaphor/o
profuse sweating
erythem/o, erythemat/o
redness
hidr/o
sweat
ichthy/o
scaly, dry (fish-like)
kerat/o
hard, horny tissue
lip/o
fat
melan/o
black
myc/o
fungus (fungi include yeasts, molds, and mushrooms)
onych/o
nail (also ungu/o)
phyt/o
plant
pil/o
hair (also trich/o)
hair follicle
rhytid/o
wrinkle
seb/o
sebum (oily secretion from sebaceous glands)
squam/o
scale-like
steat/o
fat
trich/o
hair
ungu/o
nail
xanth/o
yellow
xer/o
dry
crust
Collection of dried serum and cellular debris
cyst
Thick-walled, closed sac or pouch containing fluid or semisolid material
erosion
Wearing away or loss of epidermis
fissure
Groove or crack-like sore
macule
Discolored (often reddened) flat lesion
nodule
Solid, elevated lesion more than 1 cm in diameter
papule
Small (less than 1 cm in diameter), solid elevation of the skin
polyp
Mushroom-like growth extending on a stalk from the surface of mucous membrane
pustule
Small elevation of the skin containing pus
ulcer
Open sore on the skin or mucous membrane
vesicle
Small collection of clear fluid (serum); blister
cellulitis
Diffuse, acute infection of the skin marked by local heat, redness, pain, and swelling
eczema
Inflammatory skin disease with erythematous, papulovesicular lesions
exanthematous viral diseases
Rash (exanthem) of the skin due to a viral infection
gangrene
Death of tissue associated with loss of blood supply
impetigo
Bacterial inflammatory skin disease characterized by vesicles, pustules, and crusted-over lesions
psoriasis
Chronic, recurrent dematosis marked by itchy, scaly, red plaques covered by silvery gray scales
scabies
A contagious, parasitic infection of the skin with intense pruritus
scleroderma
A chronic progressive disease of the skin with hardening and shrinking of connective tissue
systemic lupus erythematosus (SLE)
Chronic inflammatory disease of collagen in the skin, of joints, and of internal organs
tinea
Infection of the skin caused by a fungus
vitiligo
Loss of pigment (depigmentation)in areas of the skin (milk-white patches)
callus
Increased growth of cells in the keratin layer of the epidermis caused by pressure or friction
keloid
Hypertrophied, thickened scar that occurs after trauma or surgical incision
keratosis
Thickened area of the epidermis
leukoplakia
White, thickened patches on mucous membrane tissue of the tongue or cheek
nevus (plural: nevi)
Pigmented lesion of the skin
verruca
Epidermal growth caused by a virus (wart)
basal cell carcinoma
Malignant tumor of the basal cell layer of the epidermis
Kaposi sarcoma
Malignant, vascular, neoplastic growth characterized by cutaneous nodules. Frequently on the lower extremities. Associated with AIDS
malignant melanoma
Cancerous growth composed of melanocytes
squamous cell carcinoma
Malignant tumor of the squamous epithelial cells of the epidermis
Laboratory Test:

bacterial analyses
Samples of skin are sent to a laboratory to detect presence of microorganisms
Laboratory Test:

fungal tests
Scrapings from skin lesions, hair specimens, or nail clipps are sent to a laboratory for culture and microscopic examination
cryosurgery
Use of subfreezing temperature via liquid nitrogen application to destroy tissue
curettage
Use of a sharp dermal curet (curette) to scrape away a skin lesion
electrodesiccation
Tissue is destroyed by burning with an electric spark
Mohs surgery
Thin layers of a malignant growth are removed, and each is examined under a microscope
skin biopsy
Suspected malignant skin lesions are removed and sent to the pathology laboratory for microscopic examination
skin test
The reaction of the body to a substance by observing the results of injecting the substance intradermally or applying it topically to the skin
Abbreviation:

ABCD
Characteristics assoc. with skin cancer

Asymmetry (of shape)
Border (irregularity)
Color (variation with one lesion)
Diameter (greater than 6 m)
Abbreviation:

bx
biopsy
Abbreviation:

Derm.
dermatology
Abbreviation:

DLE
discoid lupus erythematosus
Abbreviation:

PPD
purified protein derivative; skin test for tuberculosis
Abbreviation:

PUVA
psoralen-ultraviolet A light therapy (treatment for psoriasis)
Abbreviation:

SLE
systemic lupus erythematosus
Abbreviation:

subcut
subcutaneous

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