Histology- Bone
Terms
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- What is an osteoblast?
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Secretes osteoid
Not totally surrounded by bone matrix
Derived from osteoprogenitor cell and cannot undergo mitosis
- What are the 2 types of bone?
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1) Trabecular
2) Compact - What type of collagen is found in bone?
- Type I collagen for TENSILE strength
- What does bone serve as a reservoir for?
- calcium and phospate
- What are osteocytes?
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These are osteoblasts completely surrounded by self secreted bone matrix.
Found in Lacunae
Communicate via GAP JXN within canaliculi
NO MITOSIS - Ground substance is composed of?
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1) Proteoglycans with sides of GAGs
2) Glycoproteins
3) Hydroxyapatite
4) Water - What do osteoclasts look like?
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1) Reside within Howship's lacunae
2) Multinucleated - What is compact bone?
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1) No spaces visible to naked eye.
2) Forms the thick tube around long bones (Diaphysis)
3) Surrounds the medullary cavity
4) Thin layer also covers epiphysis - What do osteoclasts do?
- They resorb bone via lysosomal enzymes and collagenase
- Where is the periosteum?
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Outer layer
dense connective - Where are osteoclasts derived?
- From Monoctyes!
- What is trabecular bone?
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"Spongy bone"
1)Consists of delicate bars and sheets of bone, trabeculae.
2)Forms a spongy network.
3)Mainly found as ends of long bones (Epiphysis) - What is osteoid?
- Unmineralized bone