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How many café-au-lait spots are needed for Neurofibromatosis Type I dx
At least 6
Most common cause of nephrotic syndrome in kids
Lipoid nephrosis
Angina characterized by coronary artery vasospasm, symptom occurrence at rest, ST elevation (during episode)
Prinzmental variant angina
Decreased ACTH and no cortisol suppression with dexamethasone
Cushing’s SYNDROME (adrenal adenoma)
Congenital small bowel outpouching is a remnant of vitelline duct
Meckel diverticulum
The tea and toast diet is classically associated with what cause of megaloblastic anemia
Folate deficiency (very common in the elderly)
What bronchogenic carcinoma is assoc with hypercalcemia, involves keratin pearls, men > women, assoc with smoking, occurs in major bronchi, and is seen in the central areas of the lung
Squamous cell carcinoma
Is an anti-HAV IgG Ab associated with immunization or recent infection?
Anti-HAV IgG Abs are assoc with immunization or prior infection. Anti-HAV IgM is associated with acute or recent infection
Is Dubin-Johnson or Rotor syndrome associated with black pigmentation of the liver
Both are AR with conjugated hyperbilirubinemia, but Dubin-Johnson syndrome is differentiated from Rotor by the black pigmentation in the liver
Which form of melanoma carries the best prognosis
Lentigo maligna melanoma
Most common cause of Infantile diarrhea
Rotavirus
Lewy bodies
Parkinsons
What three chemical agents are associated with angiosarcoma of the liver
Arsenic, thorotrast, and vinyl chloride
Thickened, hyperpigmented skin in axillae, groin, and skin folds associated with malignancies, obestity and diabetes
Acanthosis nigricans
Most common Esophageal carcinoma
Squamous cell
Most common Joint affected in pseudogout
Knee
What is released from mitochondria to trigger apoptosis
Cytochrome c
Most common cause of neonatal bowel obstruction
Hirschsprung disease
3 opsonins
Fc portion of IgG, C3b, and mannose-binding proteins
20 year old woman with ptosis, diplopia, weakness in jaw muscles when chewing, and muscle weakness with repeated use
Myasthenia gravis
Acute, chronic, or hyperacute rejection of renal tx? Monthes-yrs after tx gradual onset of HTN, oliguria, and azotemia, seen as intimal fibrosis of the blood vessels and interstitial lymphocytes
Chronic rejection
What variant of polyarteritis nodosa is associated with bronchial asthma, granulomas, and eosinophilia
Churg-Strauss syndrome
What seronegative spondyloarthropathy is seen in HLA-B27-pos young men, involves sacroiliac joints, has no subcutaneous nodules, and has a bamboo spine appearance on x-ray
Ankylosing spondylitis
Eating fava beans can produce Mediterranean type of what deficiency
G-6-PD deficiency
Hematoxylin or eosin? Thyroid colloid
Eosin
What hematologic malignancy is particularly likely to affect down syndrome pts
ALL (15-20 times the normal risk)
Hep virus that is an enveloped DNA hepadnavirus
Hep B
Most common Germ cell tumor of the ovary
Dysgerminoma
What syndrome has elevated FSH and LH levels with decreased testosterone levels and 47XXY karyotype
Klinefelter syndrome
Acute, chronic, or hyperacute rejection of renal tx? Immediately after tx seen as a neutrophilic vasculitis with thrombosis
Hyperacute rejection
Most common cause of bronchiolitis in kids
RSV
Autosomal dominant disease involving hyperkeratosis of the palms and soles in association with esophageal carcinoma
Tylosis
Soap bubble appearance on x-ray
Giant cell tumor of bone
Ab used in dx’ing CREST syndrome
Anticentromere Abs (Scl-70) for dx’ing diffuse scleroderma
Most common cause of Aspiration pneuomia in an alcoholic
Klebsiella pneumoniae
What are the 3 carboxylase enzymes that require biotin
Pyruvate, acetyl CoA, and propionyl CoA carboxylasae
Most common cause of osteomyelitis in sickle cell pts
Staph aureus (but more prone to salmonella infections)
Most common Pancreatic islet cell tumor
Insulinoma
Term for hypoperfusion of an area involving only the inner layers
Mural infarct
Risk factors for cervical cancer
Multiple pregnancies, early age of intercourse, multiple sex partners, OCP use, smoking, HIV, STDs
Marfan disease associated chromosome
Chromosome 15
Most common Benign GI tumor
Leiomyoma
Cancer associated with aromatic amines and azo dyes
Hepatocellular carcinoma
Lisch nodules
Neurofibromatosis I
What disease is dx’ed by findings of ANAs and ant-SCL-70 Abs
Scleroderma
Cancer associated with polycyclic aromatic hydrocarbons
Bronchogenic carcinoma
What vitamin is needed for the production of heme
Pyridoxine (B6)
Enzyme deficiency in alkaptonuria
Homogentisic oxidase
Most common Solid tumor in kids
Neuroblastoma
CNS neurons regeneration – labile, stable, or permanent?
Permanent
Most common cause of Meningitis in immunocompromised AIDS pt’s
Cryptococcus
Angina characterized by coronary artery nonocclusive thrombus, symptom occurrence with increasing frequency, duration, intensity and decreasing activity, frequently at rest
Unstable (crescendo) angina

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