Exam 2 October 2006
Terms
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- HHNKS
- Hyperosmolar hyperglycemic non-ketotic syndrome
- Diabetes Mellitus
- Chronic disorder of altered fat, carbohydrate, and protein metabolism caused either by a relative or absolute lack of insulin or inability of tissues to respond to insulin.
- Polydipsia
- excessive thirst
- Polyphagia
- excessive hunger
- Polyuria
- excessive urination
- Lipodystrophy
- atrophy of the SC tissue
- Ketonuria
- ketones present in urine
- ICA
- Islet cell antibody
- hypoglycemia
- Low blood glucose
- hyperglycemia
- High blood glucose
- HLA
- Human Leukocyte Antigen
- Gestational diabetes
- Diabetes during pregnancy
- DKA
-
Diabetic Ketoacidosis
acidosis due to an excess of ketone bodies - Pathology of Type I DM
-
autoimmune disease triggered by environmental factors (i.e. virus)
>90% Type I have Islet Cell Antibodies (ICA) an indication of autoimmune response
Many also have Human Leukocyte Antigens (HLA)
As Islets are destroyed, ICA's and insulin antibodies increase, which lowers circulating insulin, which increases blood glucose