REPRO lab path review
Terms
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- cervical pathologies on gross test
-
LSIL (HPV 6 & 11)
HSIL (HPV 16 & 18)
Invasive Sq Cell Carcinoma (below BM) - uterine pathologies on gross test
-
Endometriosis
-young w/pelvic pain
-weird c/o (appendix, kidney)
-hemosid MPs
Endometrial Adenocarcinoma
-near menopause, extra estrogen
-glands on glands (crib)
Leiomyoma
-young, no Sx or period c/o
-extra estrogen
-mesynchymal
Leiomyosarcoma
-NOT from leiyomyoma - Ovarian pathologies on path test
-
Mucinous Adenocarcinoma of ovary
-might be GI met (krukenberg)
-pseudomyxoma peritonei
-epithelial
-nodular adnexal mass
Dysgerminoma
-germ cell
-older than men
-always malignant, good prog
-radio responsive
Teratoma
-meso (fat, musc, cart, skel)
-ecto (skin, glands)
-endo (resp, gut) - Breast path on test
-
Fibroadenoma
-young
-movable, solid mass
-stroma overgrowth
Ductal Adenocarcinoma
-older
-fixed, nodular
-mets to lymph, lung, brain - Placental path on test
-
Chorioamnionitis
-ascending or hematologic spread
-neuts in chorion are mom's
-neuts in cord are baby's (funicitis)
-E Coli & GBS - hypercellular, mitotoic figures, no glands
-
HSIL
NOT below BM - hypercellular, mitotic figures, no glands, below BM
- invasive carcinoma of cervix
-
young woman w/pelvic pain
looks like appendix or kidney
what is key finding -
Endometriosis
hemosiderin laden MPs
glands and stroma -
woman near menopause
high estrogen state
histo w/no stroma, only glands -
endometrial adenocarcinoma
cribriform glands -
young woman
high estrogen state
no sx or IVB -
Leiomyoma
(mesenchymal origin)
not precursor to LMsarcoma - cellular origin of leiomyoma
- mesenchymal
-
smooth muscle proliferation
clear boundary -
leiomyoma
(uterine path) - smooth muscle proliferation, no boundary, mitotic figures
-
leiomyosarcoma
(uterine path) -
nodular adnexal mass
pseudomyxoma peritonei -
mucinous adenocarcinoma of ovary
check bowel & appendix
EPITHELIAL - metastasis that resemlbles mucinous adenocarcinoma
-
krunkenberg
from bowel or appendix -
40 y/o woman
malignant ovarian tumor
very responsive to radiation treatment -
dysgerminoma
seminoma in men present earlier - treatment for dysgerminoma
-
radiotherapy
very successful - derivitives of mesoderm
- fat, musc, cart, skel
- derivitives of ectoderm
- skin, glands
- derivitives of endoderm
- respiratory, GI
- teratoma presentation in men
- always malignant
- teratoma presentation in women
- usually benign
- types of teratoma
-
mature- diff tissue types
immature- embrionic cells - two ways for teratoma to become malignant
-
malignant transformation of teratoma cells
composed of embrionic cells - older woman with fixed nodular lesion on breast
- Ductal Carcinoma
- breast cancer mets to
- lung & brain
- younger woman with movable solid mass in breast
-
fibroadenoma
stromal overgrowth - bugs associated with chorioamnionitis
- E coli & GBS
- placental infection
- chorioamnionitis
- severe placental infection
-
funicitis
polis in cord