BILD 2 MidTerm
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- What is IgG commonly found
- It is found in the Anitibodies and Bloodstream
- What role does FSH and LH play in the female reproductive system.
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FSH stimulates the folicle
LH Produces Estrogen and matures the Folicle - What is the Germ Line theory?
- The immune system is inherited from your parents
- Where is the IgD commonly found?
- It is found in the B-cells
- What is the function of the Seroli Cell?
- it Protects and nurishes the sperm
- Define Sarcoma
- A cancer which effects the dense tissurefibers (ie bone, muscles, and connective tissues).
- What is the Cell that protects and nurishes the sperm?
- The Sertoli Cell
- What are the three types of sexual reproduction?
- Ovipariety; Viviparity; Ovoviviparity
- Where do the Sperm learn to swim?
- Epididymus
- What are the four types of Asexual reproduction?
- Fission, Budding, Fragmentation, Parthenogenesis
- What is the pathways of developement for the Ovum?
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Primortial germ cell
Matures into a oogonium
undergoes Mitosis
Primary Oocyte
undergoes Meiosis I
Secondary Oocyte & 1st PolarBody
undergoes Meiosis II
Ovum & Secondary PolarBody - What are the parts of the Innate Immune system's first line of defense?
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1) Skin (epithelia) ~ physical barrier
2) Saliva and tears ~ they contain lysosomes which eat foriegn matter
3) Somach Acidity - What are the three ways of treating cancer?
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1)Cut it out surgically
2)Kill it with radiation
3)Kill it with chemicals - What is the type of cancer which effects the blood cells?
- Leukemia
- What are the causes of Cancer?
- Viruses; X-rays; UV radiation; Mutation
- What is the Somatic Theory?
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That immunity is develope in a part of your body.
- What is the second line of defense in the innate immune system?
- Endocytosis with the use of Phagocytes (more specifically Macrophages)
- What secretes histamines?
- Basophylls and Mast Cells
- What are the two types of tumors and what do they mean?
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Benign = noninvasive
Malignant = invasive/metastasis/moves - Define Pyrogenes
- Part of the inflammitory response, they provide a fever response.
- What is the definition of cancer?
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When cells break the rules of production and growth
- Define Endocrine glands
- Ductless glands that secrete directly into the blood.
- Where is the IgM found?
- Antibodies and the blood stream
- The ant. portion of the pituitary gland scretes two types of hormones. What are they?
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Tropic Hormones which control other glands
Non Tropic Hormones which which act directly on the cells. - Where is IgA commonly found?
- Protecing the epithelial structures
- Define Exocrine glands
- Ducted glands that go to the outside of the body
- What are the components of Lymphocytes
- There are B-cells and T-Cells
- What provides the sperm with testosterone?
- The Leydig Cells
- How does the sperm break throught the egg?
- It uses the acrosome at the tip of the sperm.
- What is special about the pituitary gland?
- It has two parts. Anterior and Posterior
- Define Carcinoma
- The cancer of the epithelia cells (ie skin cells; inner organs; and glands)
- What is structure of the antibody comprised of?
- It contains two identical heavy chains and two identical light chains. Both have a variable part and a constant part.
- The Adrenal Gland produces wha two properties?
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Epinephrine which causes flight or fight reaction
Cortico Steroids. - What is the name of the cancer which effects the dense tissure fibers?
- Sarcoma
- What are the five hallmarks of Cancer?
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T - Tissue invasion/metastasis
A - Avoidance of Apoptosis
I - Independance of Cell Regulation
L - Limitless replication potential
S - Sustained Angiogenesis - Define Leukemia
- The Cancer of the blood
- What were the examples given of non-tropic hormones?
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Growth hormones
Enkephlans
Endorphines - Define a Spermatogonia
- It is what the primortial germ cell matures into.
- Define the Oviparity
- Egglaying
- Define Lymphoma
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The caner which effects the lymphatic system
- What are the two components of the adaptive/cell mediated immune response?
- Lymphocytes and Antigens
- What are the five classes of Immunogloblins?
- IgM, IgE, IgG, IgA, IgD
- Define Autocrine
- A self activating duct.
- Define Cytokines
- Part of the inflammitory response, they send out beacons for phagocytes
- How many copies of the mutated gene do you need to have a tumor in Tumor Suppresors, and why?
- You need two because this is the loss of function of cell death.
- Define palpatation
- Touch
- What are some strategies adopted by viruses.
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Drift and shift = move and mutated
Latency = lay dormant until host has lowered immunity. - Tumors are said to be clonal. What does that mean?
- The mass of cells all came from one single cell being replicated/ Cloned
- Tumors are said to be heterogenous. What does that mean?
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they are mutated in many ways
- What is the name of the cancer which effects the lymphatic system?
- Lymphoma
- define an epitope
- An epitope is the finger print of a cell upon which T-Cells inspect each cell.
- What is the difference between MHCI and MHCII?
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MHCI is found in all cells, uses the CD8 co-receptor, and flags down cytotoxins (T killer cells)
MHCII is found in B-cells and Macrophages, uses the CD4 co-receptor, and uses T helper cells which allows Antibodies to be made.
- What is the third line of defense in the innate immune system
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Inflammitory
1) Cytokines send out beacons for Phagocytes
2) Pyrogenes provide a fever response
3) Histomines Increasing blood flow and # of phagocytes - What component of a sperm provides the energy to swim?
- The mitochondria at the base of the tail
- Where is the IgE commonly found?
- The GI tract and the airways.
- When the Follicle burst what does it release?
- The Secondary Oocyte
- What is the pathway of spermatogenesis?
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Primortial Germs Cell
matures to a SPERMATOGONIA
undergoes Mitosis
Primary Spermatocyte
undergoes Meiosis I
Secondary Spermatocyte
undergoes Meiosis II
Spermatids -
What are the two genes that give rise to cancer?
- Proto-oncogenes and Tumor Suppressors
- Define Paracrine glands
- A gland which effects neighbors
- Define Negative Selection and what is it used for?
- This selects everything that is not signaling. This is used to telling the immune system of what is yours and what isn'. The body kills all T and B cells which register when one is young.
- What is the name of the cancer which effects the epithelia cells?
- Carcinoma
- What does the Antibodies do to fight invaders?
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1) Neutralize the Toxins by finding the active site and breaking it
2) Opsonization - which is flaging down phagocytes. - What happens to the burst follicle?
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It forms a Corpus Luteum which releases progesterone(Preventing the sheding of the endometrium).
- Difine Ovoviviparity
- All the nurishment comes from a closed egg like structure yet it is housed in the mother for added protection.
- Where does the sperm mature?
- The Semineferous tubules
- How many copies of the mutated gene do you need to have a tumor in Protooncogenes, and why?
- You only need one because it gains the function of limitless replication.
- FSH and LH are examples of what type of hormone?
- Tropic
- What are the two sub sets of vivparity?
- Marsupials and placentals
- What is the Leydig cell responsible for?
- It provides testosterone for the sperm.
- What are the factors of making up the variable portion of an antibody?
- Varible section, Diversity Section, the joining section, and then the constant part
- What is the role of FSH and LH in the male reproductive system?
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FSH stimulates Sertoli
LH stimulates Leydig - What is the definition of Contact inhibition?
- When a normal cell comes into contact with another cell it stops growing.