MLA
Terms
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How much blood does a human have?
What is the compositon of Blood? -
5 Liters
Cellular Elements suspended in fluid, Plasma - What percentage of blood volume is Plasma?
- 50% - 60%
- What is Plasma?
- A complex solution in which blood cells are suspended. It contains sodium, chloride, amino acids, oxygen, hormones, and vitamins.
- What percentage of plasma is water?
- 90%
- How does the quality control in hematology differ from quality control in other lab departments?
- Standards are not available, and is not possible with blood cells since it is a living tissue.
- What is the only substance measured in Hematology?
- Hemoglobin. The hematology lab must rely on commercial control solutions.
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Define the following:
Erythrocytosis
Leukocytosis
Thrombocytosis -
Excess of RBC also Polychthemia
Increase of WBC above normal
Abnormal increase in the number of platelets in the blood - What are the cellular elements of blood?
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Erythrocytes - RBC
Leukocytes - WBC
Thrombocytes - Platelets - How long does Erythrocytes live?
- 120 days.
- Conditions that cause hematological diseases are:
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Anemia - RBC too low
Leukemia - WBC production out of control
Thrombocytopenia - Low platelet count - Describe inherited hematological diseases:
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Hemophilia - Bleeding problems due to the bloods inability to clot; the coagulation factor is missing.
Sickle Cell Anemia - abnormal hemoglobin function causes by structure. - Compare accuracy and precision of manual and automated blood cell counting methods.
- Manual Counts coefficient of 10%...Automated is 1-3%
- Name the Five types of Leukocytes.
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Never Let Monkeys Eat Bananas
Neutrophils 60%
Lymphocytes 30% Immunity
Monocytes 6%
Eosinophils 3% Allergy Attack
Basophils 1% Histamine - What are GRANULOCYTES?
- A type of white blood cell responsible for engulfing and digesting micro-organisms. Granulocytes consist of three types of phagocytic, or cell-eating, cells: basophils, eosinophils and neutrophils
- What are AGRANULOCYTE
- A type of white blood cell; monocytes and lymphocytes are agranulocytes
- Define Platelet
- Platelets are irregularly-shaped, colorless bodies that are present in blood. Their sticky surface lets them, along with other substances, form clots to stop bleeding
- What is the function of platelets?
- When bleeding from a wound suddenly occurs, the platelets gather at the wound and attempt to block the blood flow. The mineral calcium, vitamin K, and a protein called fibrinogen help the platelets form a clot.
- What does plasma contain?
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The plasma contains salts and various kinds of proteins, hormones, Sodium Na+
Potassium K+
Calcium Ca
Chloride Cl-
Hydrogen Carbonate HCO3-
Phosphate - What is serum
- The clear, thin and sticky fluid portion of the blood that remains after coagulation. Serum contains no blood cells, platelets or fibrinogen
- Plasma contains?
- Clotting agents such as fibrinogen
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What color tube for Serum?
What color tube plasma -
Red Top Tube
Light Blue/EDTA - What six things are in a CBC?
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White blood cell (WBC) Incease means Bacterial, and decrease is viral.
White blood cell differential looks at the types of white blood cells present.
Red blood cell (RBC) count is a count of the actual number of red blood cells per volume of blood.
Hemoglobin measures the amount of oxygen-carrying protein in the blood.
Hematocrit measures the amount of space red blood cells take up in the blood.
The platelet count is the number of platelets in a given volume of blood. Both increases and decreases can point to abnormal conditions of excess bleeding or clotting
RBC Morphology = Anemai types