MCD Bio 40 UCLA
Terms
undefined, object
copy deck
- Globally Ratio of Men:Women with Aids
- 1:1
- Surrogate markers used for Drug regimesn
- T-4 Lymphocyte coute and viral load
- Highest HIV exposure category in the World is:
- Men who have sex with women, because of Africa
- The receptive partner is at greater risk of HIV infection the the insertive partner
- True
- What is Condoms efficent rate in the prevetion of AIDS/HIV
- 80-90%
- What is the Greatest risk factor for getting HIV/AIDS (what body fluid)
- BLOOD
- Side effects of AZT are:
-
* anemia (a drop in your red blood cells that can make you feel tired or short of breath)
* leukopenia ( a drop in your white blood cell that can increase your risk of bacterial infection).
* headache
* fatigue
* dizziness
* stomach upset
* muscle aches
* colour change in your nails
* difficulty sleeping - When placebos are used in phase II clinical trials, today, patients in this group are given the best available treatment against the diseased being tested
- True,
- People with terminal illnesses are turning away for Traditional medicine and going to alternative therapies
- True
- The predominant clinical manifestation that occurs during the clinical course of the HIV infection is
- A gradual decrease in CD-4 lymphocytes
- According to the CDC which racial groups are proportionally over represented in the AIDS case in america.
- Blacks and Hispanics
- According to the CDC who are the highest exposed category to HIV/AIDS in america.
- 1. Men who have sex with men
- During fallatio the receptive partner is at greater risk of HIV infection then the insertive partner.
- True
- Anthropologists have shown a correlation between male ______ and HIV tranmission in Afica.
- circumcision
- HIV can be transmitted by insect bite
- false
- Dry sex in regions of Africa increase the rate of HIV tranmission.
- True
- Protease inhibitors target which component of the HIV life cycle.
- assembly of the HIV virus.
- If a organism makes 35 proteins how many genes must it have/
- 35
- Who was President of the US during the AIDS out break
- Reagan
- Why is there an increse risk of HIV tranmission in places like Aferica.
- High levels of STDs, Sexual rituals that invole exchange of blood, lack of womens rights, people moving from small villiges to large citys.
- Expression of which HIV gene is demonstrated to cause AIDS related demenia, in transgenic mice.
- ENV (GpP120)
- Making RNA from DNA is called
- Transcription
- Makeing DNA from RNA is called
- Translation
- Being infected and having a T4 count lower then ______ will give you a diagnosis of AIDS
- 200
- What ancient pharaoh is given responsible for the AIDS epidemic
- King Tut (bogas)
- In America, what year did the death rate begin to decline due to better drugs and treament.
- 1995
- Which Swedish scientist is given credit for starting the feild of taxonomy.
- Linnaeus
- Who designed the Compassionate Plea program
- David Kessler
- Mutations in HIV are heritale changes in the sequence of what?
- DNA
- A monomer of RNA is called a
- nucleotide
- Phylogenetic trees for retroviruses were created by comparing sequence homologies of
- DNA
- Physician were intially afraid of HIV becuase it was transmitted in a similat fashion to?
- Hepatits
- when a B cell matures is becomes plasma and secretes?
- antibodies
- Is HIV testing mandatory for all pregnant mothers
- NO
- what does it cost to do drug testing and approval of the FDA
- 200 million
- ________ is a statictical examination and characterization of an epidemic or disase.
- epidemiology.
- Is AIDS a rural or urban disease
- Urban
- HIV-2 is in what part of africa
- west
- In america what is the average to get diagnosis with AIDS
- 30-40 yrs.
- How many people globally are impacted with HIV
- 40 million
- How many g rituals enes does HIV have?
- 3
- Why is AIDS a bigger problem globally, then in america
- breast feeding, different levels of infected women, sex rituals
- when a virus lays dormant in an infected cell, it is called?
- lysogenic
- what phase of clincal trials monitors the efficacy of the drug in question ageaist a specific disease
- II
- T cells requires which of the following organs to mature during development.
- Thymus
- What steps in HIV life cycle are single out for targets for drugs
- Reverse transcription and the assembly of core proteins
- What birth controll pill in the 1960 gave daughters cervical cancer.
- Diethylstilbesterol
- In the 1980's what meathod of AIDS tranmission was eliminated.
- blood tranfustion.
- AIDS is cased by what
- Retrovirus
- An Epidemiology is:
- The branch of medicine that deals with the study of the causes, distribution, and control of disease in populations. *Determine risk factors*
- If a female is infected with HIV during intercorse, which of her cells most likely will be infected.
- Langerhan cell
- What type of cells are invouled in immune responce
- Lymphocytes, macrophages, CD-4 cells, and killer cells (check for B cells)
- When a B cell binds to its antigen it undergoes
- Differentiation(maturation), clonal amphlification divison, and phagocytosis.
- What type of lymphocytes does HIV infect
-
CD-4 lymphocytes, red blood cells, killer cells,
B lymphocytes - major side effects of drugs used to target HIV :
- muscle and never pain, anemia, diarrhea
- how many strands does typical DNA have
- 2
- What generalized compinent of th immune responce is most important in makeing a vaccine
- memory
- The magic bullet is in referece to:
- syphilis paul ehrlich 1910
- When was the Golden Age of MicroBiology
- 1900's
- When was the Golden Age of Molecular biology
- 1950's
- What phase of clinical trials needs consent
- phase I,II and III
- LD-50 is determined in phase
- I and maybe II
- AZT interfers with what part of the HIV life cycle
- revers transcription
- Which arm of the immune responce requires DIRECT help for a CD-4 lymphocyte
- B cells
- The primary immune response is slower then the secondary immune responce
- False
- A CD-8 cell becomes a
- KILLER CELL
- Probability of contraction aids by anal sex
- 1/100
- lymphocyte secrete a hormone know as:
- lymphokine
- What could be used as a possable vaccine aginst HIV
- Attenuated (weakened) HIV, GP-120, part of GP-120, a gene for ENV put in a non-disease producing virus.
- When a CD-4 Cell matures it learns to:
- HELP
- Something your body recongnizes as non-self is called a(n)
- Antigen
- The reeptive vaginal intercours the most likely cekk to be infected by HIV is a CD-4 lymphocyt.
- False
- Who is the Cal. Berkeley professor who believes the AIDS is not cause by HIV.
- P. Duesberg
- Which drugs are targeted to specific steps of the life cycle of HIV
- Protease inhibitors
- When a antigen meets the appropriate lymphocyte is case that lymphocyte to under go
- clonal amplification and differentiation
- the formation of a syncitium (a cluster of multinucleate cells) is one way that HIV kills uninfected cells
- true
- which type of lymphocyte is directed towars intracellular antigens
- CD-8
- What book help shape Americans drug testing policy
- The Jungle by Upton Sinclair
- Who was the Surgeon General during Reagans appoint.
- C.E. Koop
- What is a defination of a desease
- A break down of the reflex arc
- phagocytosis is cellular what?
- Eating
- The B cell receptors in a single B cell are homogeneous.
- True