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Ch. 12 A.N.S.

Terms

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ANS
innervates all effector organ except skeletal muscle cells.
involuntary control system
Subdivided into :
Parasympathetic
Sympathetic

Most organs are innervated by BOTH subdivisions

Tend to act in opposition to one another.

Tend to be active under different conditions

Primary goal of ANS is to maintain homeostasis

during activity, SNS dominates control.
Autonomic neurotransmitters & receptors
2 receptors secreted by a target cell

PNS - Ach (acetylycholine)
SNS - NE
Cells that secrete Ach - cholenergic
Cells that secrete NE - adrenergic
PNS
____ - Ach (acetylycholine)
NE
SNS - ___
cholenergic
Cells that secrete Ach - ___________
adrenergic
Cells that secrete NE - ___________
neurotransmitters
receptor type determines which _____________ will act on target cells.

cholinergic - respond to Ach
adrenergic - respond to NE
Cholenergic receptors
2 subclasses
Nicotinic
Muscarinic
Nicotinic
receptor that is found on postganglionic dendrites and cell bodies, in the adrenal medulla, on skeletal muscle cells, and recently have been found in small regions of the CNS.

receptor act to open Na+ or K+ channels
Muscarinic
found on effector organs controlled by the PNS

receptors act as part of a G protein system to open or close ion channels.
Adrenergic receptors
2 subclasses located on target cells

alpha
beta
Alpha receptors
Activate or inhibit 2nd messengers

May act to DECREASE cAMP activity

Can be effected by both NE and E from adrenal medulla.
Beta receptors
Act on G proteins systems to INCREASE cAMP activity.

Can be activated by both NE and E.

Deck Info

13

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