Pharm 3
Terms
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- DOC for Viridans strep (endocarditis)
- PCN G
- DOC for Treponema palladium (syphylis)
- PCN G
- DOC for Strep A, C, and G pharyngitis
- PCN V
- PCN used for non-compliance
- Bicillin
- PO impetigo or cellulitis from S. aureus; Strep Gp A
- Dicloxacillin (anti-staph PCN)
- PCN effective against GNB incl H. influenzae
- Ampicillin IV; Amoxicillin Oral
- Infected wounds /c sepsis; peritonits s/p bowel perf
- Unasyn
- Otitis media resistant to Amoxi; sinusitis; animal bites; inf wounds
- Augmentin
- PCN that extend Ampicillin to include Pseudomonas aeruginosa and other GNB
- Piperacillin and Ticarcillin
- B-lactam inhibitors comb /c other PCNs
-
Clavulanic acid
Sulbactam
Tazobactam - ceph used for skin infx by S. aureus; Gp A strep
- Cephalexin (Keflex)
- DOC ceph for surgical prophylaxis
- Cephazolin (Ancef)
- ceph option for resistant OM; alt for CAP and pharyngitis
- Cefaclor (Ceclor)
- ceph used for /a /p surg of abdomen
- Cefoxitin (Mefoxin)
- alt ceph in OM and resistant sinusitis
- Cefpodoxime (Vantin)
- DOC for N. gonorrhea urethritis; also used for resistant OM, meningitis, pharyngitis
- Ceftriazone (Rocephin)
- cephs used for severe GNB ifx incl meningitis, endocarditis
-
Cefotaxime (Claforan)
Ceftazime (Fortaz) - empiric tx for febrile neutropenia and some strains of enterobacter
- Cefepime (Maxipime)
- works against GNB only; B-lactamase resistant
- Aztreonam (Azactam) - monobactam
- 1st line for enterobacter, pseudomonas, serratia, febrile neutropenia, sever resistant ifx (xreax /c PCN)
- carbapenems (imipenem /c cilastatin; meropenem; ertapenem)
- narrow spectrum GPB; restricted used MRSA; pt /c B-lactam allergy or life threatening C. dif colitis
- vancomycin
- synergistic effects when used /c aminoglycosides against E. faecium and faecalis
- vancomycin
- PO only for C. dif colitis
- vancomycin
- vancomycin renal and ototoxic effect increase /c?
- aminoglycosides
- topical use glycopeptide used for GPB
- bacitracin
- topical used for impetigo, S. aureus, Gp A Strep, MSSA, and MRSA
- Mupirocin (Bactroban)
- Rx for Rocky Mtn spotted fever; typhus in children <8 (rickettsia)
- Chloramphenicol (Chloromycetin) or Coxycycline (Vibramycin)
- DOC for abd surgery
- Ampicillin
- DOC for gonorrhea
- Rocephin(R)
- Gen of cephs used for severe gram neg ifx
- 3rd Gen
- beta lactam w/ low cross reactivity
- aztronam (azactam) - beta lactamase resistant; gm neg only
- broadest available spectrum drugs used if resistant to -cillins and cephs-
- carbapenems (imipenem, meropenem, ertapenem)
- carbapenems have a __% cross reactivity w/ pcn
- 50%
- Alt drug if MRSA, B-lactam allergy, or PO for C. difficile colitis
- vancomycin
- what drug causes red man/neck syndrome if given too fast?
- vancomycin
- DOC for vancomycin resistant enterococcus faecium (VREF)
-
synercid (IV)
zyvox (PO) -
Alt drug for vancomycin
Used for staph, strep, and vanc-susc E. faecalis - Daptomycin (Cubicin)
- grey teeth SE caused by
- tetracycline
- grey baby syndrome caused by
- chloramphenicol
- -cycline DOC for renal impairment
- doxycycline
- doxycycline DOC for
- CARL is living w/ goats in the rocky mountains and gets lyme dz from the fleas, anthrax from the pelts, and the clap from the animal lovin' (chlamydia, anthrax, rmsf, lyme dz)
- macrolide for H. inf
- clarithromycin
- macrolide for legionnaires
- erythromycin
- macrolide that must be taken w/ food
- erythromycin
- macrolides used for CAP
- azithromycin and telithromycin (ketek)
- which macrolide causes C. dificile overgrowth
- clindamycin (cleocin)
- DOC for tx c. dificile overgrowth?
- Metronidazole or PO vancomycin
- adverse rxns of aminoglycocides
- ototoxicity and nephrotoxicity
- DOC for OM prophylaxis?
- sulfonamide - sulfisoxazole (gantrisin)
- DOC for non-infected burns?
- silver sulfadiazine (silvadene)
- DOC for prostatitis >35yo?
- FQ or Bactrim
- DOC for uncomplicated UTI in child?
- Bactrim
- DOC for pneumocystis carinii pneumonia (PCP)?
- Bactrim
- Which antifolate drug if sulfa allergy?
- Trimethroprim
- SE of trimethroprim?
- megaloblastic anemia (due to folate deficiency)
- DOC for inflammatory bowel dz (ulcerative colitis, Crohn's Dz)?
- sulfasalazine (azufidine)
- DOC for suppurative conjunctivitis?
- Polytrim
- which gen of FQ best for gram neg?
- 2nd gen FQ
- "-floxacin"?
- FQ
- "-mycin", "-micin"?
- macrolides and aminoglycosides
- "-cycline"?
- tetracyclines
- "cef-" or "ceph-"?
- cephalosporins
- "-cillin"?
- penicillins
- Indications for FQs?
- UTI, prostatitis, gonorrhea, inf diarrhea, CAP, alt for bronchitis, sinusitis, skin ifx
- CI for FQs?
- prego and <18yo (due to cartilage erosion)
- CI for Nitrofurantoin use?
- G6PD deficiency
- prophylaxis for UTI when?
- >3 UTIs/yr (Nitrofurantoin)
- DOC to control burning assoc w/ UTI?
- Pyridium
- anti-Tb drugs incl?
-
"RIPES"
Rifampin
Isoniazid
Pyrazinamide
Ethambutol
Streptomycin - which anti-tb drug CI in preg?
- streptomycin
- MC nosocomial fungal pathogen?
- candida albicans
- DOC for vanginal candidiasis?
- Fluconazole
- dose of fluconazole to tx vaginal candidiasis?
- 150mg x1 dose
- DOC for fungal ifx in immunocompromised?
- Vfend
- monitor ? when using Vfend?
- liver, renal, and visual disturbances
- DOC for finger and toenail fungal ifx?
- lamisil
- DOC for oral thrush?
- Nystatin
- DOC for tinea corporis and tinea pedis?
- clotrimazole 1% (lotramin)
- hallmark of malaria treatment?
- prophylaxis
- primary anti-malarial if chloroquine resistance?
- malarone
- anti-malarial DOC for preg?
- mefloquine
- anti-malarial DOC for aviators?
- Doxycycline
- used to tx uniform for 50 washes against mosquitoes?
- permthrin impregnation kit (IDA)
- which antivirals used for influenza?
- amantadin, rimantadine, relenza(R) and tamiflu(R)
- which antivirals used for prophylaxis?
- amantadine and rimantadine
- which flu antiviral used for treatment only?
- relenza and tamiflu
- DOC for herpes (all)?
- acyclovir (zovirax)
- Famciclovir is the prodrug for ?
- Penciclovir
- OTC top agent for herpes labialis?
- abreva
- DOC for HIV and Hep B?
- Lamuvidine (3TC, Epivir)
- DOC for post exposure to HIV needle stick?
- Zidovudine and Lamivudine; add Indinavir if large exposure