Antihistimines and antiinflammatories

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Aspirin like agent indomethacin: Indocin
dose: 25-50 mg q8-12h
max 200mg qd
aspirin like agent choline magnesium trisalicylate: Trilisate
dose: 1-1.5 g q12h
max 4g qd
aspirin like agent sulindac: Clinoril
dose: 150-200mg q12h
max 4g qd
aspirin like agents meclofinamate: Meclomen
dose: 50-100mg q4-6h
max 400mg qd
Nonsteroidal Antiinflammatory Drugs (NSAIDS) aspirin: Bayer
dose: 325 to 1000 mg q4-6h
max 4g qd
NSAID's ibuprofen: Motrin, Advil
dose: 300-800mg q6-8h
max 3.2 g qd
NSAID's naproxen: Aleve
dose: 275-500mg q12h
max 1.25g qd
NSAID's Naproxen sodium: Anaprox
dose: 250-500mg q12h
max 1.5 g qd
NSAIDS ketoprofen: Orudis
dose: 12.5-75mg q6-8h
max 300mg qd
NSAID's flubiprofen: Ansaid
dose: 50-100mg q6-12h
max 300mg qd
NSAID's ketorolac: Toradol
dose: 15-60mg q6h (IM or IV)
10mg q6h (po)
max 120mg qd (IM, IV, or po)
NSAIDs fenoprofen: Nalfon
dose: 200mg q4-6h
max 3.2g qd
NSAIDs oxaprozin: Daypro
NSAIDs nabumetone: Relafen
dose: 1g q12-24h
max 2g qd
NSAIDS etolodac: Lodine
dose: 200-400mg q6-12h
max 1.2g qd
Cyclooxygenase Inhibitors (COX-2) inhibitors celcoxib: Celebrex
dose: 100-200mg q12-24h
max 400mg qd
Cyclooxygenase Inhibitors (COX-2) inhibitors valdecoxib: Bextra
Corticosteroids prednisone: Deltasone
ind: for the treatment of a wide variet of diseases such as adrenocortical insufficency and respiratory, GI and neoplastic diseases. also used for allergic inflammatory and autoimmune conditions.
given on tapered dosing schedule so body will make glucocortiroids again.
route: po tab, sol, syr.
Corticosteroids methylprednisolone: Solu-Medrol, Medrol
ind: antiinflammatory or immunosupressive agents used to treat a variet of diseases; also used after bone marrow transplants
route: inj as acetate or sodium succinate; tab dose pack, with tapered dosing
Bronchodilators (Asthma Agents) short acting beta-2 agonist metaproterenol: Alupent
adult dose: 1 puff po q4h
route: po, inh
action: relaxes bronchial smooth muscle. specifically affects beta-2 sites
bronchodilators (asthma agents) triamcinolone acetonide: Azmacort (inhalant), Aristocort (top), Kenalog (aerosol), Nasacort (nasal)
ind: adreanocortical insufficency, rheumatic disorders, allergic states, respiratory diseases and other diseases requiring antiinflammatory or immonosuppressive effects; nasal spray: treatment of seasonal allergic rhinitis; inhalation control of bronciahl asthma and related broncho-spastic conditions
route: tab, syr, aerosol, spray, inj as acetonide, diacetate, or hexacetonide
shake well
corticosteroid (asthma agents) flunisolide: AeroBid
adult dose: 2 sprays in each nostril bid
route: nasal
action: inhibits certain enzymes that are responsible for inflammation stabilizes lysosomal membranes
shake well
corticosteroid (asthma agents) fluticasone: Flovent
adult dose: 1 puff po bid
route: inh
action: inhibits certain enzymes taht are resonsible for inflammation stabilizes lysosomal membranes
corticosteroids (asthma agents) budesonide: Pulmicort
adult dose: 1-2 puffs po bid
route: inh
action: inhibits certyain enzymes thatere responsible for inflammation stabilizes lysosomal membranes
1st Generation Antihistimine diphenhydramine: Benadryl
action: used to decrease inflammation and irritation from allergens
forms: cap, tab, sol, inj
ind: allergies, sedation
>>drowsiness
1st generation antihistimine chlorpheniramine: Chlor-Trimeton
1st generation antihistimine cyproheptadine: Periactin
1st generation antihistimine clemastine: Tavist
2nd Generation antihistimine fexofenadine: Allegra
2nd generation antihistimine cetirizine: Zyrtec
2nd generation antihistimine loratadine: Claritin
2nd generation antihistamine hydroxyzine: Atarax, Vistaril
Immune Cells antibodies: antibodies are produced by B lymphocytes in response to an antigen. Memory cells previously produced increas in population to fight off infection. Found in the blood. Can neutralize or destroy antigens in different ways such as by coating or lysing the antigen. They can stimuate phagocytosis and prevent the antigen from adhering to host cells.
Immune cells Fibrinogen: a fibrinogen is a globulin found in blood plasma. it helps in coagulating blood.
immune cells granulocytes: granulocytes are mature leukocyte cells that contain granules. including neutrophils and other types of immune response cells. granulocytes fight off infection
immune cells Leukocytes: Leukocytes are white blood cells formed in bone marrow, including graulocytes and nongranulocytes. Leukocytes fight off infection and tissue damage. they destroy foreign organisms and also clean up damaged cells by phagocytosis.
immune cells lymphocytes: lymphocytes are white blood cells formed in the spleen and bone morrow. They adhere to endothelial cells: intensify inflammation by causing direct cell injury and promoting formation of antibodies that increase the inflammatory process
Immune cells Monocytes: Monocytes are a large type of leukocytes that eventually become macrophages. Macrophages are one of the first line of defenses in the inflammatory process.
immune cells neutrophils: neutrophils are mature white blood cells in the granulocytic series, comprise more than 50% of the leukocytes present in the body. they adhere to damaged site to protect agains infection by destroying infectious microbes; also destroy antigens
immune cell macrophage: a macrophage is a large cell called a phagocyte that secrete cytokines. macrophages injest dead tissue, bacterial cells or dying cells.
steroidal agent hydrocortisone " acetate " butyrate " cypionate " sodium phosphate " valerate " sodium succinate: Cortef (po), Hytone (top), Kenalog (aerosol), Anusol-HC (supp), Cortenema (enema), Solu-Cortef (inj)
ind: (po) mgmt of adrenocortical insufficency, relief of inflammation of dermatosis, and adjunctive treatment of ulcerative colitis, supp for hemorrhoids
route: inj, aerosol, ung, cr, lot, tab, sol, syr, susp
short acting beta-2 angonist asthma agent albuterol: Proventil, Ventolin
ind: bronchitis, emphysema, or asthma
adult dose: 1-2 puffs po q4-6h
route: po, inh
action: relaxes bronchial smooth muscle specifically affects beta-2 sites
>>lightheadedness, increased heart rate
short acting beta-2 agonists asthma agent isoetharine: Brokosol
ind: bronchitis, emphysema, or asthma
adult dose: 1-2 puffs po q4h
route: inh
action: relaxes bronchia smooth muscle specifically affects beta-2 sites
>>lightheadedness, increased heart rate
short acting beta-2 agonists asthma agent pirbuterol: Maxair
ind: bronchitis, emphysema, or asthma
adult dose: 1-2 puffs po q6h
route: inh
action: relaxes bronchial smooth muscle specifically affects beta-2 sites
>>lightheadedness, increased heart rate
short acting beta-2 agonists asthma agent epinephrine: Adrenalin
ind: bronchitis, emphysema, or asthma
adult dose: 1-2 puffs po qid
route: SC, inh
action: relaxes bronchial smooth muscle specifically affects beta-2 sites
>>lightheadedness, increased heart rate
short acting beta-2 agonist asthma agent isoproterenol: Isuprel
ind: bronchitis, emphysema, or asthma
adult dose: 2-3 puffs po q3-4h
route: inh, IV
action: relaxes bronchial smoothe muscles specifically affects beta-2 sites
>>lightheadedness, increased heart rate
short acting beta-2 agonists asthma agent terbutaline: Brethine
ind: bronchitis, emphysema, or asthma
adult dose: max 12 qd
route: po, inh, IV
action: relaxes bronchial smooth muscle specifically affects beta-2 sites
>>lightheadedness, increased heart rate
Corticosteroid beclomethasone: Vanceril, Beclovent, Vacenase
adult dose: inh 2 puffs q6-8h
nasal: 1 spray in each nostril qid
route: inh, nasal
action: inhibits certain enzymes that are responsible for inflammation stabilizes lysosomal membranes
shake well
Anticholinergic asthma agent ipratopium bromide: Atrovent
ind: asthma
adult dose: 1-2 puffs bid
route: neb
action: inhibits certain enzymes thate are responsible for inflammation stablilizes lysosomal membranes
Leukotriene agonist asthma agent montelukast: Singulair
ind: asthma
adult dose: 10mg po qd, 4mg and 5mg chew tabs for peds
route: po, chew tab
action: reduces bronchioconstriction of airways. also given to prevent asthma attacks triggered by allergic antigens if taken before contact is made. blocks leukotriene receptors, stops anaphylaxis
Tk utd
leukotriene agonist asthma agent Zafirlukast: Accolate
ind: asthma
adult dose: 20 mg po bid
route: po
action: reduces bronchioconstriction of airways. also given to prevent asthma attacks triggered by allergic antigens if taken before contact is made. blocks leukotriene receptors, stops anaphylaxis
Tk utd
leukotriene agonist asthma agent zileuton: Zyflo
ind: asthma
route: po
action: reduces bronchioconstriction of airways. also given to prevent asthma attacks triggered by allergic antigens if taken before contact is made. blocks leukotriene receptors, stops anaphylaxis
Tk utd
Xanthine agents asthma agents theophylline: Theo-Dur, Slo-bid
ind: asthma, bronchial disorders
action: works on smooth muscle of bronchioles
route: po, inj
forms: tab, cap, syr, elixir, sol, SRtab, SRcap, inj
Tk c food
do not crush or chew tablets
Tk utd
Xanthine agent asthma agent aminophylline: Phyllocontin
ind: asthma and bronchiole disorders
action: works on the smooth muscle of the bronchioles
route: po, inj, supp
forms: tab, liq, supp, inj
Tk c food
do not chew or crush tablets
Tk utd
antiasthmatic and antiallergic agent cromolyn sodium: Intal
ind: severe bronchial asthma, prevention of exercise-induces bronchospasm, allergic rhinitis
route: inh, nasal
action: prevents mast cells from releasing histamine. can prevent allergic reactons if taken before contact with the allergen
nasal inhaler avl OTC
forms: inh sol, aerosol spray, nasal sol, cap for inh
shake well

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