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Test 2

Terms

undefined, object
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Pain is what type of reaction?
protective
What are pain receptors called?
nociceptors
What tissue does not have pain receptors?
nervous tissue
What is fast pain called
neospinothalmic pain
What neuronal fibers are fast pain?
Group III alplha delta afferents
What kind of pain is fast pain?
localized and short
Where does alpha delta afferent fibers terminate?
rexed lam I
What rexed lams does alpha delta afferent fibers and c afferents?
I, II, V
What do second order fast pain neurons do?
decussate to thalmus
Where do third order fast pain neurons project to?
3-1-2 of cortex
What is slow pain called?
paleospinothalmic pain
What neuronal fibers are slow pain?
Group IV C afferents
What kind of pain is slow pain?
poorly localized associated with chronic pain
When does "second pain" occur?
after adelta sensation , prolonged suffering , nausea , vomiting (follows fast pain)
Which kind of pain and which fibers have high threshold for mechano and thermoreceptors?
paleospinothalmic pain , group IV c afferents
What are the branches of the c afferents?
spinomesencephalic , spinoreticular
What do spinomesencephalic neurons do?
nociceptive information involved with moving eyes relative to source of noxious input
What does spinoreticular and paleospinothalmic fibers do?
arousal , withdrawal , autonomic , affective responses to pain
What type of fibers are Alpha Beta?
mechanofibers
Where do alpha beta branches go?
rex lam II
What does rex lam II secrete?
substance P
Where is PAG located?
midbrain
What do spinreticular secrete?
beta endorphin enkephalin
What does activated PAG pathways do?
inhibits dorsal horn cells pain response , mediates opioid analgesia , activates raphe nuclei in pons
What does ralphe nuclei do?
release serotonin into dorsal horn through the corticospinal tract stimulating rex lam II
What are the 2 main receptors of the GSA system?
proprioreceptors , sensory
Which of the following stements regarding C-fibers (group 4 afferents) is correct
when activated, produce diffused activating pain
Lightly rubbing a recently bruised elbow will result in which of the following
produces analgesia or a decrease in pain intesity
Which of th following statements regarding nocioceptors with A-delta axons is/are correct
they mediate the sharp , fast component of pain
Prostaglandins, leukotriens, 5-HT, histamine, IL-1,2,10 and TNFa all excite
C
which of the following does not excite nociceptors in the skin?
beta endorphins
what stimuli activate group IV afferent fibers
slow pain
What is the function of the A efferent fibers
Motorneuron innervations to the extrafusal fibers
Based on the meta analysis of Staiger et al, 2003......., what did not appear to be beneficial
Serotonin selective reuptake inhibitors
Which of the following does not promote excitation of nociceptros in the skin
Free protons, prostaglandins, histamine, bradykinen...answer was all of them
What neurotransmitter from the brainstem is derctly responsible for modulation of pain signals
serotonin
Both fast pain and slow pain travel primarily within what tract of the spinal cord
Spinothlamic (anterolateral system)
Which pathway of the cord conveys unconscious proprioception from the upper limb
cuenocerebellar
primary site for spinal cord modulation is
rex lam V
what are the so called gate keepers in pain
substantia gelatinosa
What type of fiers predominate the dorsal spinocerebellar tract
GP
What is the location of a cell body of the alpha-motor neuron
rexed 9
Where do alpha motor neurons terminate
extrafusal muscles
Which of the tracts are not related ot the anterolateral system
ventral corticospinal
Which neurotransmitter within the brainstem is INDIRECTLY responsible for modulation of pain signals
norepinephrine
Proprioception from the leg is conveyed via
dorsal spinocerebellar tract,medial lemnicus, inferior cerebellar peduncle
where do spinoreticular fibers terminate?
PAG
nucleus z is related to what tract?
dorsal spinocerebellar
the spinal lemiscus contains the spinothalmic tract?
true
clarkes column houses the second order perikarya for what tract?
dorsal spinocerebellar
The second order perikarya neruons for the spinothalmic tract are found in what lamina?
rexed V
pain transmission is impeded due to destruction of rexed II?
false
The dorsal columns contain what tracts
neither dorsal spinocerebellar or rubrospinal
Which of the following stements regardint he spinothalamic tract is correct
it crosses the midline at the spinal cord
Which of the following best completes the stement, the fasciculus gracilis originates in the spinal cord and is......?
apart of the dorsal column and medial lemniscus tract
which of the following is not in the lateral funiculus?
fasciulus cuneatus
clark's column houses what 2nd order perikarya?
ventral spinocerebellar
Projections from the reticular midbrain raphe neurons to the dorsal horn of the spinal cord actely suppress the conscious awarenss of pain use which of the following neurotransmitters
serotonin
fine touch of arm
funiculus cuneatus
Three major divisions of the anterolateral system
spinothalmic , spinoreticular , spinotectal
Given that interruption of a reflex arc is in the efferent limb, which is not a site at which the problem may be located
lateral corticospinal tract
Which of the following is true regarding nerve conduction velocity
alpha alpha>alpha beta>alpha gamma>alpha delta (Aα > Aβ > Aγ > Aδ)
where do the clark's column fibers terminate?
cerebellum
Brachial plexus notes posterior divsion innervation to the little finger
radial
brachial plexus notes flexor innervation to the middle finger
median
not innervated by brachial plexus
triceps
muscolotaneus
c5, c6, c7
Lateral cutaneous nerve of the tigh is related to what dermatome?
l3
innervates musculature of the lower foot and leg?
sciatic
What roots are related to sciatic n.?
l4-s3
brown-sequard lesion would result it?
contralateral loss of pain sensation inferior to lesion
duchenne palsy
not median or c5-c7
anterior division nerve innervates?
gracilis
GSA and GVA innervation from the abdomen both travel in what pathway?
dorsal columns and anterolateral
staiger and spine
meta analysis
slow and fast pain travel in?
spinothalmic
staiger and spine what was beneficial
tricyclic antidepressants
where do alpha motor neurons originate?
rex lam ix
What spinal levels is clarks column found at?
t1-l3
What is found in the intermediolateral gray?
sympathetics
What spinal level is the intermediolateral gray found at?
T1-L3 and S2-S4
Where do substantia gelatinosa neurons project to and form?
through anterior white commisure to anterior spinothalmic tract
Where do clark's column axons form?
ipsilateral posterior spinocerebellar tract
What tracts are in the lateral funiculus?
lateral corticospinal tract, rubrospinal tract, dorsal spinocerebellar, anterolateral system
What does lateral corticospinal tract do?
descending 85% of axons, motor innervation to limbs
rubrospinal tract?
facilitates limb flexion
dorsal spinocerebellar?
unconscious proprioception, kinesthia
Where does gentle/noxious stimuli come from?
rex lam v
Medial lemniscus conveys what?
contralateral cuneatus and gracilis
Where do the spinal roots get their blood supply from?
radicular arteries
What reinforces the anterior artery
anterior segmental medullary artery
What reinforces the anterior artery in the lumbrosacral region only?
artery of adamkeiwitz
lou gehrigs
rex lam ix
spinoreticular tract terminates where?
PAG
Large anterior horn cells are located in what rex lam?
ix
obturator?
hip abductors
do gsa and gva share a common pathway?
yes
Lateral cutaneous nerve dermatome?
l3
Medial lemniscus is what kind of neuron?
GSA
Sciatic posterior nerves innervate what muscles?
anterior extenson
sciatic anterior nerves innervate what muscles?
posterior flexors

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