Chlamydia
Terms
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- what is special about chlamydia that affects treatment
- no peptidoglycan layer so can't be treated with penicillin
- why is chlamydia an obligate intracellular organism
- needs ATP
- what are the two forms of chlamydia
- elementary body and reticular body
- C pneumonia is refered to as the?
- TWAR STRAIN
- what percent of the US seroconverts with Chlamydia pneumonia
- 30-50 is infected and can seroconvert when their immune system is comp
- what is c pneumonia associated with
- atheroscleritic plaque
- C. psittaci is associated with?
- influenza or pneumonia from pet birds
- C. trachomatis is associated with is associated with?
- eye and genital infection
- what are the serotypes associated with disease (serotypes are based on outer membrane differences)
- A-L
- what is trachoma infection serotype
- A, B, C
- Trachoma infection is common where?
- middle east, pacific Islands, Asia
- how does trachoma work
- lymphoid follicles form turning the eyelids inward and scarring the cornea with the eyelashes
- Inclusive conjunctivitis involves what serotypes
- D-K
- what is inclusive conjunctivitis
- mucopurulent discharge 2-25 days following birth resolves slowly over a few months
- what is inclusive conjuntivits associated with
- neonate pneumonia, afebrile, low mortality
- non-gonococcal urethritis is associated with what serovars
- D-K
- what is the most common non-gonococcal urithritis
- chlamydia 30-50%
- how much more common is chlamydia than gonnorhea
- 2-3 x
- what percent of males are asymptomatic
- 10%
- what percent of people are coinfected with chlam and gon
- 30%
- how long does gonorrhea take to show up? how long does chlamydia
- gon takes 2-7 days chlam takes 2-3 weeks
- does gonorrhea or chlamydia have bacteria in the exudate
- neither
- chlamydia can cause ? in women
- cervicitis which may progress to PID in 8% and can be associated with third trimester abortions
- LGV (lymphogranuloma venereum) serovars?
- L1, L2, L3 only 300/year in US mostly in africa, asia, south america
- how does LGV present
- inguinal Buboes
- Chlamydia is associated with what syndrome/sequela
- Reiters (arthritis, conjunctiva, urethritis)
- how do you diagnose chlamydia
- ELISA, IF confirm with culture and PCR
- epidemiology of chlamydia
- 6 million cases of blindness, 10-40% of african children are infected
- what is the response to chlamydia
- humoral
- treatment
- doxycycline or azithromycin NOT SILVER NITRATE