fluids 6
Terms
undefined, object
copy deck
- where are oat cell carc cells where one cell seems to be capping anoth, causing n to look quarter moon likely to be diagnostic of
- metastatic bronchogenic oat cell carcinoma
- when diffuse malig mesothelioma consists of both histologic types,what is it said to be
- biphasic
- what cytologic features help recognize malig meso
- lg nos that look mesothelial, many cs discrete but clusters numerous, large cells but may have low n/c,N round or oval with smooth contours,chromatin fiinely stippled,Prominent Ni
- in what adeno carc in fluids has most extensive vacuolization
- ovary and lung
- are there more than one type sm cell anaplastic nonlymphomatous neoplasms
- yes oat,wilms' and neuroblastoma
- what is anaplastic
- Of, relating to, or characterized by cells that have become less differentiated./ A term used to describe cancer cells that divide rapidly and have little or no resemblance to normal cells.
- technique to tell meso from adeno
- immunochem
- why is it easy to determine that neoplastic cells have mesothelial lineage
- reproduce non-neoplastic features of benign
- in which fluids is it most likely to find sq carc cells
- pleural
- what color may a fluid be that contains numerous heavily pigmented melanoma cells
- chocolate brown,with clear light yellow supernatant
- 2 histologic types diffuse malig mesothelioma
- epithelial and sarcomatous
- when are adenos in fluids most likelly to be isolated cells with only occasional cluster
- carc of stomach and some breast,esp lobular type
- what is the only type of diffused malig meso that can be found cytologically
- epithelial
- what is growth pattern of malig mesotheliomas
- simultaneous on both meso layers,first as tiny nodules,that fuse forming thick rind that oblilterates serous cavity
- why would you want to avoid thoracotomy or laparotomy when have mesothilioma
- mesos have tendancy to grow into thora or lap scars
- are melanoma cs in fluid usually heavily pigmented
- no usually lt dusting brown cyto pig to none
- are adeno cells in fluids vacuolated
- most, but some have few on no vacuoles
- what are clues to mesothelioma
- amt of indiv cs and cllusters and larger cell size-more than hypertrophy or hyperplasia
- can malig meso develop in any serous cavity
- yes
- what is best ex of ananplastic carc in serous fl
- metastatic sm cell-oat cell
- what is architecture of adenos in serous fluids
- cells may be solitary,clusters of few cells, large papillary frags, or speroids of hundreds of cells
- what is most common cavity for malig meso
- pleural
- describe n of mesothelioma
- round or oval with smooth countours and stippled chromatin prom Ni
- what is a feature that may help make diag of mesothelioma vs benign
- large no of cells individual and clusters and large average size of cells
- a type of carc whose cs may resemble stack of coins
- oat(sm cell)
- what locations are most likely adenos in effusions from
- breast,lung or ovary
- are proliferation spheres solid or hollow
- can be either focussing gives impression of hollow
- are urothelial carc cells found in fluids
- rarely
- why is it desirable that a cytologic diag of mesothelioma be made
- to avoid thoracotomy or laparotomy scars
- what adeno in fluid characterized by signet ring cells, with lg cyto vacuoles and eccentric N
- gastric
- what is appearance of fluid with high concentration of hyaluronic acid in mesothelioma
- viscosity like honey
- what is 2 step process in diag of mesothelioma in serous fl
- 1-determine are meso 2-decide if malignant(not so easy)
- may sq carc in pl fl be keratinized on nonK
- both
- what are well-circumscribed spheroids of adeno of fairly uniform cells called
- proliferation spheres
- how does size sm cell anaplastic(oat cell) carc cells compare to lymphocytes
- about 2xs size of lmphocytes
- what inhaled entity may cause malig mesothilioma
- asbestos
- what are classic features of adeno
- tendency for large,smooth clusters ,eccentric malignant-appearing n, prom Ni,vacuolated cyto
- what is stippled
- dots and flicks
- describe melanoma cells in serous flulids
- round,about sz or larger than meso cs,discrete or maybe clusters:abundant cyto with brown pigment:central or eccentric N: may have lg Ni: some may have vacuole whhich is an invagination of cyto
- is it common to find sq carc cells in effusions
- no
- do pts with advanced melanoma produce serous fluids
- frequently
- do cells exfoliated from malig meso have obvioius n features of malig
- no
- where are adeno cells with tiny cyto vac with central dense mucus spot, like bull's eye, lined by microvilli likely to be from
- breast, esp lobular type
- where are proliferation spheres most likely to be derived from
- breast
- what is most likely origin of sq carc cells found in serous fluid
- lung or upper resp tr
- is diffuse malig mesothelioma common or rare
- rare
- what is def of supernatant
- The soluble liquid reaction of a sample after centrifugation or/ the usually clear liquid overlying material deposited by settling, precipitation, or centrifugation precipitation of insoluble solids.
- how do mesotheliomas relate to the layers of mesothelium
- develop simultaneously on both layers of mes