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Ch.21 Pharmacology

Terms

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SERM
-Selective Estrogen Receptor Modulator

-with estrogen like effect on bones and fat.
sedative
a mildly hypnotic drug that relaxes without necessarily producing sleep.
respiratory
treats asthma, emphysema, and infections of the respiratory system.
purgative
strong carthartic
progestin
female hormone that affects the lining of the uterus during pregnancy.
narcotic
habit-forming drug (potent analgesic) that relieves pain by producing stupor or insensibility.
laxative
weak cathartic
hypnotic
produces sleep
glucocorticoid
hormone from the adrenal cortex that raises blood sugar and reduces inflammation.
gastrointestinal
-relives symptoms of diseases in the gastrointestinal tract.

-examples are antacids, antiulcer drugs, cathartics, laxitives, purgatives, antinauseants, antidiarrheal drugs.
estrogen
female hormone responsible for secondary sex characteristics.
endocrine
-a hormone or hormone like drug.

-examples are androgens, estragens, progestins, SERM, thyroid hormone, andglucocorticoids.
pt
patient
gm
gram
gtt
drops
h
hour
h.s.
at bedtime
HRT
Hormone Replacement Therapy
caps
capsule
cc
cubic centimeter
_
c
with
b.i.d.
two times a day
ad lib
freely as desired
a.c.
before meals
vas/o
vessel
vit/o
life
toxic/o
poison
thec/o
sheath (of brain and spinal cord)
prurit/o
itching
pyret/o
fever
pharmac/o
drug
or/o
mouth
narc/o
stupor
p.o.
by mouth
p.r.n.
when requested (required)
stimulant
-excites and promotes activity.

-examples are caffeine and amphatamines.
p.c.
after meals
thyroid hormone
stimulates cellular metabolism
myc/o
mold, fungus
lingu/o
tongue
hypn/o
sleep
esthes/o
feeling, sensation
erg/o
work
cras/o
mixture
alges/o
sensitivity to pain
aer/o
air
emetic
promotes vomiting
tranquilizer
controls anxiety and severe disturbances of behavior
diuretic
increases the production of urine and thus reduces the volume of fluid in the body; antihypersensitive.
cardiovascular
-acts on the heart and blood vessels.

-this catagory of drug includes ACE inhibitors, beta blockers, calcium antagonists, diuretics, and cholesterol lowering drugs.
calcium antagonist
-blocks the entrance of calcium into the heart muscle and muscle lining of blood vessels.

-used as an antiarrhythmic, antianginal, and antihypersensitive.

-calcium channel blocker.
beta-blocker
blocks the action of epinephrine at sites on receptors of heart muscle cells, the muscle lining of blood vessels, and bronchial tubes.
cathartic
relieves constipation
caffeine
central nervous system stimulant.
bisphosphonate
prevents bone loss in osteoporosis
bacteriostatic
inhibits bacterial growth
bactericidal
kills bacteria

(-cidal means to kill)
aromatase inhibitor
reduces the amount of estrogen in the blood.
6 parenteral injections
1. Intracavitary
2. Intradermal
3. Intramuscular
4. Intrathecal
5. Intravenous
6. Subcutaneous
antipruritics
against itching
antiviral
acts against viruses such as the herpesvirus and HIV.
antiulcer
inhibits the secretion of acid by cells of the lining of the stomach.
antiplatelet
reduces the tendency of platelets to stick together.
antinauseant
relieves nausea and vomiting; antiemetic
antihisamine
blocks the action of histomine and helps prevent symptoms of allergy.
antiemetic
prevents nausea and vomiting
antidiarrheal
prevents diarrhea
antidiabetic
drug given to prevent or alleviate diabetes meltitus.
antidepressant
releives symptoms of depression
anticonvulsant
prevents convulsions
anticoagulant
prevents blood clotting
antibiotic
chemical substance produced by a plant or microorganism that has the ability to inhibit or kill foriegn organisms in the body.
cardiotonics or antiarrhythmie
treats abnormal heart rythms.
antiandrogen
slows the uptake of androgens or interferes with their binding in tissues
antacid
neutralizes acid in the stomach
angiotensin II

receptor antagonist
lowers blood pressure by preventing angiotensin from acting on receptors in blood vessels.
anesthetic
reduces or eliminates sensation; general and local.
androgen
male hormone
analgesic
relieves pain
amphetamine
central nervous system stimulant
ACE inhibitor
-Angiotensin Converting Enzyme inhibitor
-lowers blood pressure.
-blocks the conversion of angiotensin I to angiotensin II (a powerful vasoconstrictor)
vitamin
substance found in foods and essential in small quantities for growth and good health.
United States Pharmacopeia (U.S.P.)
Authoritive list of drugs, formulas, and preparations that sets a standard for drug manufacturing and dispensing.
transport
movement of a drug across a cell membrane into body cells.
toxicology
the study of harmful chemicals and their effects on the body.
toxicity
harmful effects of a drug
topical application
drugs applied locally on the skin or mucous membranes of the body; ointments, creams, and lotions are applied topically.
tolerance
becoming resistant to the action of a drug as treatment progresses, therefore, larger drug doses must be given to achieve the desired effect.
syringe
instrument (tube) for introducing or withdrawing fluids from the body.
synergism
combination of two drugs causes an effect that is greater than the sum of the individual effects of each drug alone.
sublingual administration
drugs are given by placement under the tongue.
side effect
toxic effect that routinely results from the use of a drug.
rectal administration
drugs are inserted through the anus into the rectum.
receptor
target substance with which a drug interacts in the body.
Physicians' Desk Reference (PDR)
reference book that lists drug products.
pharmacology
study of the preparation, properties, uses, and actions of drugs.
pharmacologist
specialist in the properties, uses, and actions of drugs.
pharmacokinetics
calculation of drug concentration in tissues and blood over a period of time.
pharmacodynamics
study of the effects of a drug within the body.
pharmacy
Location for preparing and dispensing drugs; also the study of preparing and dispensing drugs.
pharmacist
prepares and dispenses drugs.
parenteral administration
drugs that are given by injection into the skin, muscle, or veins (any route other than through the digestive tract).
oral administration
drugs that are given by mouth.
molecular pharmacology
study of interaction of drugs and subcellular entities such as DNA, RNA, and enzymes.
medical chemistry
study of new drug synthesis; relationship between chemical structure and biological effects.
inhalation
administration of drugs in gaseous or vapor form through the nose or mouth.
vasodilator
when vessels widen to increase blood flow and lower blood pressure.
vasoconstrictor
when vessels shrink causing blood flow to decrease and increasing blood pressure.
APAP
acetaminophen (tylenol)
H2 blocker
histamine H2-receptor; antagonist
MAOI
Monoamine Oxidase Inhibitor; antidepressant
PCA
patient controlled administration
SSRI
Selective Serotonin Reuptake inhibitor; antidepressant.
TCA
Tricylic antidepressant
sig.
let it be labeled
_
S
without
SL
sublingual
S.O.S.
if necessary
sc
subcutaneous
tab
tablet
t.i.d.
three times a day.
Q(q)
every
q.d.
every day
q.h.
every hour
q.h.s.
every bedtime
q.i.d.
four times a day
idiosyncrasy
unexpected effect produced in a particularly sensitive individual, but not seen in most patients.
iatrogenic
condition caused by treatment (drugs or procedures) given by medical personel.
generic name
legal non-commercial name for a drug.
Food and Drug Administration (FDA)
Governmental agency having the legal responsibility for enforcing proper drug manufacture and clinical use.
contraindications
factors in the patients condition that prevent the use of a particular drug or treatment.
chemical name
chemical formula for a drug
brand name
commercial name for a drug; trademark.
antidote
agent given to counteract and unwanted effect of a drug.
antagonistic action
combination of two drugs gives less than and additive effect (action)
anaphylaxis
exaggerated hypersensitivity reaction to a drug or foreign organism.
aerosol
particles of drug suspended in air.
additive action
drug action in which the combination of two similar drugs is equal to the sum of the effects of each.
addiction
physical and psychological dependence on, and craving, for a drug.
6 ways to administer drugs
1. Oral
2. Rectal
3. Sublingual
4. Parenteral
5. Inhalation
6. Topical
qns
quantity not sufficient
q.s.
sufficient quantity
qAM
every morning
qPM
every evening
IM
intramuscular
IV
intravenous
mg
miligram
NPO
nothing by mouth
NSAIDs
Non-Steroidal Anti-Inflammatory Drug.
oz.
ounce
-mycin
mold
laparoscopy
-visual examination of the abdominal cavity.

-other names are:
*peritoneoscopy
*MIS (minimally invasive surgery)
achondroplasia
an inherited disorder in which the bones of the arms and legs fail to grow to normal size because of a defect in both bone and cartilage. (dwarfism)
acromegaly
-endocrine disorder.

-occurs when the pituitary gland produces and excessive amount of growth hormone after the completion of puberty.
mon/o
one
eosin/o
rosy
bas/o
basic
diplococci
-berry-shaped bacteria organized in pairs.

-examples are pneumocci (bacterial pneumonia), and gonococci, which invade the reproductive organs causing diarrhea.
abscess
a collection of puss, white blood cells, and protein that is present at the site of infection.
gon/o
seed
hernia
a protrusion of an organ or the muscular wall of an organ through the cavity that normally contains it.

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