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Autoantibodies and disease

Terms

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Antinuclear antibodies (ANA)
SLE
Anti-dsDNA
specific for SLE
Anti-Smith
specific for SLE
Anti-histone
specific for drug-induced lupus
(caused by:
Hydralazine, INH, Phenytoin, Procainamide)
Anti-IgG
Rheumatoid arthritis (autoantibody also known as rheumatoid factor)
Antineutrophil
Vasculitis
p-ANCA
Polyarteritis Nodosa
1. necrotizing degeneration of media --> aneurysms
2. small and med arteries
3. ass'd w/ Hep B
c-ANCA
Wegener's Granulomatosis
1. necrotizing, granulomatous lesions in kidney and lung
2. small arteries and veins
3. cough, ulcers of nasal septum, RBC casts
Anticentromere
Scleroderma (CREsT)
Calcinosis
Raynaud's
ESophageal dysfn
Telangiectasia
Anti-Scl-70
Scleroderma (diffuse)
Antimitochondrial
Primary Biliary Cirrhosis (PBC)
Antigliadin
Celiac sprue
Anti-basement membrane
Goodpasture's Syndrome
Anti-epithelial cell
Pemphigus vulgaris
Antimicrosomal
Hashimoto's thyroiditis
(anti-thyroglobulin and anti-thyroid peroxidase)

Deck Info

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