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final drug cards


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PROTONIX(pantoprazole) MAY ALTER THESE Laboratory Values
SGPT, creatinine increased, hypercholesterolemia, and hyperuricemia. transaminase elevations
theophylline, cisapride, antipyrine, caffeine, carbamazepine, diazepam (and its active metabolite, desmethyldiazepam), diclofenac, naproxen, piroxicam, digoxin, ethanol, glyburide, an oral contraceptive (levonorgestrel/ethinyl estradiol), metoprolol, nifedipine, phenytoin, warfarin (see below), midazolam, clarithromycin, metronidazole, or amoxicillin
PROTONIX (pantoprazole),
Patients treated with proton pump inhibitors and warfarin concomitantly should be monitored for increases in INR and prothrombin time.
PROTONIX (pantoprazole),
Serious Adverse Events
include retinal detachment, iatrogenic traumatic cataract and endophthalmitis
PROTONIX (pantoprazole),
Common Adverse Events
Bronchitis, diarrhea, headache, dizziness, nausea
PROTONIX (pantoprazole),
Common Adverse Events 6-10%
6-10% Bronchitis, diarrhea, headache, dizziness, nausea
PROTONIX (pantoprazole),
Common Adverse Events 1-5%
Arthritis, chest pain, dyspepsia, hearing loss, vertigo, vomiting, contact dermatitis
WHAT IS pantoprazole (Protonix) AND WHAT DOES IT DO?
Proton Pump Inhibitor,
Total inhibition of gastric acid secretion
Proton Pump InhibitorS WHAT ARE SOME?
lansoprazole Prevacid),omeprazole (Prilosec),rabeprazole (Aciphex),pantoprazole (Protonix),esomeprazole (Nexium)
Proton Pump Inhibitors:
Therapeutic Uses ?
GERD maintenance therapy
Erosive esophagitis
Short-term treatment of active duodenal and benign gastric ulcers
Zollinger-Ellison syndrome
Treatment of H. pylori-induced ulcers
Proton Pump Inhibitors:
Nursing Implications ?
Assess for allergies and history of liver disease, May increase serum levels of diazepam, phenytoin, and cause increased chance for bleeding with warfarin
Angiotensin-Converting Enzyme Inhibitors
(ACE Inhibitors)?
Large group of safe and effective drugs
Often used as first-line agents for CHF
and hypertension
May be combined with a thiazide diuretic
or calcium channel blocker
ACE Inhibitors, Side Effects
Fatigue Dizziness
Headache Mood changes
Impaired NOTE: first-dose hypotensive effect may occurtaste
Name some ACE inhibitors
Capoten/Captopril, Vasotec/Enalapril, Lotensin/Benzapril
What does an ACE inhibitor do?
Lowers periperal vascular resistance without increasing cardiac output, cardiac rate and cardiac contractility
Name some Beta Blockers
Inderal/Propranolol, Tenormin/Atenolol, Lopressor/Metroprolol
Opioid Analgesics (ei:MORPHINE): Side Effects
Nausea and vomiting
Respiratory depression
Urinary retention
Diaphoresis and flushing
Pupil constriction (miosis)
Opioid Analgesics:
Nursing Implications
Should VS change, patient’s condition decline,
or pain continue, contact physician immediately.
Respiratory depression may be manifested by respiratory rate of less than 12/min, dyspnea, diminished breath sounds, or shallow breathing.
Heparin Route and Dosage
Bolus dose: 5000units I.V., then 20-40 thousand units continuously
Prophylaxis of embolism: 5000 units s.q. every 12 hrs.
Contraindicated in persons with active bleeding
Heparin: adverse reactions
Spontaneous bleeding
Injection site reactions
Hypersensitivity reactions
Heparin: Nursing Implications
Must be given on time.
S.Q. route: 25 guage needle, apply pressure, no massage
Patient has to be weaned off continuous infusion
Oral anticoagulant started 3-5 days before I.V. infusion discontinued.

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