Goodman Hypothalamo-piuitary unit
Terms
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Posterior pituitary hormones
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ADH (vasopressin): decrease water excretion
Increase blood pressure
Oxytocin: Pregnancy and lactation
stimulates milk ejection, contraction of uterine
myometrium
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What's in the glycoprotein family?
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TSH
LH
FSH
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What's in the somatomammotropin family?
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GH (or somatotropin)
liver, muscle
prolactin
mammary gland
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What's in the POMC family?
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ACTH (adrenocorticotropin)
Adrenal cortex
Beta endorphin
MSH
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Classical hypophysiotropic hormones characteristics
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have both releasing and inhibiting hormones
All but one are small peptides
PIH (dopamine) is the exception.
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Which classical hypophysiotropic hormones influence more than 1 ant. pit. hormone?
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GnRH
Somatostatin (GHIH)
TRH
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Which hormones are controlled by more than one hypothalamic hormone?
Their net hypothalamic control?
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GH - stim
TSH - stim
prolactin - inhib
- Anterior pituitary hormone families
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Glycoprotein: large, sugar moiety alpha subunits the same; different beta subunits. hCG
Somatomammotropin: single ancestorial gene. hCS
POMC: same biosynthetic pathway