This site is 100% ad supported. Please add an exception to adblock for this site.

Physics of Anesthesia - exponential func., diffusion, osmolarity

Terms

copy deck
rate of change determined by quantity
exponential process
examples of exponential processes
thermal dilution CO measure
replacement of N2 in lungs w/ O2
anesthetic removal from body
3 compartment distribution of a drug is reflected in a washout curve with...
3 exponential processes, each reflected as a tangent off of the decay curve
steep early portion of decay curve
rapid elimination phase
shallow tail of decay curve is a function of...
metabolic processes
cool liquid holds (more/less) gas
more...because doesn't have energy to escape surface
volume of gas dissolved in 1 volume of liquid at 1 atmosphere
Bunsen solubility coefficient
Ostwald and Bunsen solubility coefficients and partition coefficient all depend on...
temperature
volume of gas dissolved in 1 volume of liquid
Ostwald solubility coefficient
Ostwald solubility coefficient differs from Bunsen how?
independent of pressure
ratio of amt of substance in two phases of equal volume
partition coefficient
ED50 (effective dose in 50%) of anesthetic
MAC (minimum alveolar conc.)
potency of anesthetics is proportional to...
solubility in oil
at the end of one time constant, what percentage remains? two time constants? three?
37%, 13.5%, 5%
FA/FI
fraction alveolar concentration/
fraction inspired concentration
one Avogadro's number of particles of solute that cannot diffuse through a semipermeable membrane
one osmole
the pressure which will prevent osmosis of a solvent into a solution
osmotic pressure
1 GMW or 1GAW dissolved in 22.4L of water (0 degrees C) has osmotic pressure =
1 atm
1 GMW of a gas expands at STP to what volume?
22.4 L
37C 1mOsm/L has osmotic pressure
19.3 mmHg
blood:gas partition coefficient 37C

enflurane
1.91
blood:gas partition coefficient 37C

halothane
2.3
blood:gas partition coefficient 37C

isoflurane
1.4
blood:gas partition coefficient 37C

methoxyflurane
12
blood:gas partition coefficient 37C

nitrous oxide
0.47
blood:gas partition coefficient 37C

sevoflurane
0.60
blood:gas partition coefficient 37C

desflurane
0.42

Deck Info

27