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C. dipth, A. haem, M. catt, Entero, Mycopl


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Elicits immune response that causes tough, adherent PSEUDOMEMBRANE formation in throat
Corynebacterium diphtheriae
"Name agent for following Diagnostic proc A. Tellurite plate
grows black colonies B. Selective medium culture
-poor growth on tellurite C. ""Fried eggs"" on culture "
"A. C. diphtheriae
B. Arcanobacterium Haemolyticum
C. Mycoplasma pneumoniae"
Underdiagnosed cause of PHARYNGITIS in older children and young adults
Arcanobacterium haemolyticum
"Virulence Factors
A. Exotoxin that inhibits protein synthesis by binding adding ADP ribose to EF-2
B. Protein P1: adheres to epithelium of respiratory tract
C. Produces DNAase enzymes and butyrate esterase "
"A. Corynebacterium diphtheriae
B. Mycoplasma pneumoniae
C. Moraxella Catarrhalis"
T/F: Mycoplasma pneumoniae stains purple on gram stain
FALSE: Mycoplasma pneumoniae has NO CELL WALL --->NO GRAM STAIN
Arcanobacterium haemolyticum is a close relative of ________?
Corynebacterium (used to be called Corynebacterium haemolyticum)
T/F: A domain of Diphtheriae AB toxin binds to cell surface receptors
"FALSE: ""A domain is catalytic and Adds ADP ribose to EF-2.
B domain Binds to cell surface receptors"
Name the members of the family Enterobateriaceae
"E. coli
Proteus mirabilis
""Serratia BurPs ProtEin in Providence and got /E. Coli""
(BurPs= Burkholderia and Pseudomonas
ProtEin= Proteus and Enterobacteria
Providence= Providencia)"
A. Aerobic, gram - rod common in soil and moist environments (water, hospital respirators, humidifers)
A. Burkholderia Cepacia
B. Aerobic, non-lactose fermenting gram -rod which is OXIDASE positive (differentiates it from other members of the Enterobacteriaceae family)
B. Pseudomonas Aeruginosa
Which of these is not part of the normal flora in humans? Serratia Marscecens, Moraxella Catarrhalis, Arcanobacterium haemolyticum
Arcanobacterium haemolyticum
T/F: Pencillin G is an effective treatment for Pseudomonas aeruginosa
FALSE: P. aeruginosa is NATURALLY RESISTANT to a variety of antibiotics **little pre-pharm pearl: use Piperacillin/ Ticarcillin to treat (B-lactam derivatives of penicillin)***
"Name agent for each associated dz
A. ""Cepacia"" syndrome and Fulminant pneumonia
B. Atypical Walking Pneumonia
C. Bullous Myringitis
D. ""Bull neck"" lymphadenopathy
E. Pharyngitis a
"A. Burkolderia cepacia
B. Mycoplasma pneumoniae
C. Mycoplasma pneumoniae
D. Corynebacterium diphtheriae
E. Arcanobacterium haemolyticum
F. Enterobacteriaceae"
What two agents are the leading causes of pneumonia and UTIs in cystic fibrosis patients?
"Name agent for each vaccine
A. LOS (lipoligosaccharide) vaccine under development)
B. Inactivated toxoid vaccine usu given in combination with tetanus toxid and pertussis vaccine"
"A. Morexella Catarrhalis
B. Corynebacterium diphtheriae"
"Name agent and the COLOR of the gram stain that you would see
A. Club-shaped rod in V or L formations that look like Chinese characters; METHYLENE BLUE reveals granules
B. ""Coryneform/diphtheriod"" rod that is a Facul
"A. Corynebacterium diphtheriae; PURPLE (GRAM +)
B. Arcanobacterium Haemolyticum; PURPLE (GRAM +)
C. Moraxella catarrhalis: PINK
(GRAM -)
D. Burkholderia cepacia; PINK
(GRAM -)
E. Mycoplasma pneumoniae; NO GRAM STAIN!! ;-)"
The DNA of this organism is part of a bacteriphage (virus!) that integrates it into bacterial chromosome and synthesizes an exotoxin
"Corynebacterium diphtheriae
(toxin = AB toxin)"
How would you treat a patient suffering from flu-like symptoms, toxic appearance, painful pharyngitis, and pronounced "bull neck" lymphadenopathy?
Immediately give ANTITOXIN that neutralizes unbound toxin in blood
Hospitalize and Isolate patient
Give Erythromycin (Antibiotic) to kill bacteria
***20% mortality if untreated**"
How would you treat a patient suffering mild PHARYNGITIS and cervical lymphadenopathy, and has virus-like symptoms?
"Patient infected with Arcanobacterium haemolyticum
Give Erythromycin (Antibiotocs)
***readily treatable***"
"Name the agent for the following dz:
A. Third leading cause of ACUTE SINUSITIS
B. Laryngeal nerve palsy
C. Fulminant pneumonia with symptoms similar to pseudomonas
D. Community-acquired pneumonia common in younger patients (10-1
"A. Moraxella catarrhalis
B. Corynebacterium diphtheriae
C. Burkholderia cepacia
D. Mycoplasma pneumoniae"
T/F: Penicillins and Cephalosporins effectively treat M. pneumoniae
FALSE: Mycoplasma pneumoniae has no cell wall, so B-lactams and cephalosporins, which inhibit cell wall synthesis, are ineffective
"A. Aerobic, Non-spore forming gram + rod with metachromatic-staining granules
B. Enteric, gram - rod similar to Klebsiella pneumoniae; forms red-pigmented colonies
C. smallest bacteria capable of growth and reproduction outside a cell; re
"A. Corynebacterium diphtheriae
B. Serratia marcescens
C. Mycoplasma pneumoniae"
T/F: E. Coli, a gram - rod, produces an exotoxin that can cause septic shock, bloody diarrhea, and UTIs
FALSE: E. coli is gram (-) enterobacteriacae; therefore produces ENDOTOXIN that causes sepsis and ENTEROTOXINS that cause diarrhea; UTIs are caused when E. coli ascends into urethra
Higly motile gram - rod that produces UREASE and is Indole +.
Providencia rettgeri
T/F: Members of the family Enterobacteriacae are major causes of Urinary Tract Infections and sepsis
T/F: Conjuctivitis, keratitis, and bronchopneumonia are 3 pathologies associated with Moraxella Catarrhalis

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