Drugs for Fun II
Terms
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- dopamine's indications? what receptors does it act on?
- d1 and d2. raise bp d1: renal vascular dialator - > diaresis
- whta type of receptor does phenylephrine work on? what are its indications?
- a-1 agonist. nasal decongestant, hypotension, atrial tachycardia, dialate pupil, local vasoconstriction
- receptor that conidine acts on? indications?
- a-2 agonist. treat hypertension. shuts down NE release.
- what receptor does dobutamine work on? whta indications?
- short term treatment of heart failure. b1 agonist
- what are the side effects of dobutamine?
- tachycardia,hypertension, arrythmia
- what are the side effects of terbutaline?
- bronchospasm, emphysema, asthma, chronic usuage gets b1 response
- what receptor does b2 act on?
- b2 agonist
- what does the law of mass action describe?
- competition between agonist and antagonist. [agonist]/[antag]
- an intrinsic sympathomimetic activity is full ag, partial or antagonist?
- partial agonist
- describe prazosin receptor action and adverse reactions?
- a1 antagonist. a non selective a1 antagonist causes tachycardia. dont know what that means forreal... its just in my notes
- propranolol is a non selective or selective beta or alpha antagonist?
- non selective beta antagonist
- timolol treats what?
- glaucoma
- name a beta one antagonist?
- metoprolol
- does metoprolol exhibit first pass effects?
- yes
- beta blockers what have indications?
- antihypertensive, antiarrythmia, antianginal, hyperthyroid, glaucoma, anxiety
- what are some side effects of beta blockers?
- bradycardia, lethargy, heart blocks that lead to heart failure, no more glucose conversion, hypoglycemia
- do beta blockers have withdraw problems when the drug is stopped?
- yes and supersensitivity can occur.
- what is the benefit of an inverse aonist?
- preserves receptors and maintains function