GU Pharm
Terms
undefined, object
copy deck
- Furosemide
- Loop Diuretic
- Bumetanide
- Loop Diuretic
- Toresemid
- Loop Diuretic
- Ethacrynic Acid
- Loop Diuretic
- Hydrocholdothiazide
- Thiazide Diuretic
- Metolazone
- Thiazide Diuretic
- Chlorthalidone
- Thiazide Diuretic
- Spironolactone & Eplerenone
-
Aldosterone Antagonists
K-sparing Diuretic - Triamterene
- K-sparing Diuretic acting on Principal cells
- Amiloride
- K-sparing Diuretic acting on Principal cells
- Mannitol
-
Osmotic Diuretics
- increases ICP, treats cerebral edema - Tolvaptan
-
Vasopression antagonist
- treats hyponatremia - sulfamethoxazole
-
Antimetabolite
- decreases the incorporation of PABA into folic acid - Trimethoprim
-
Antimetabolite
- prevents DHF --> THF
(inhibits folic acid) - Ciproflaxin
-
Fluoro-quinolone
Affects nucleic acid metabolism
Gram - at DNA gyrase - Gentamicin
-
Aminoglycoside
Cause code misreading in 30s
Only Gram - bugs - Amikacin
-
Aminoglycoside
Cause code misreading in 30s
Only Gram - bugs - Tobra/Strepto/Neo-mycin
-
Aminoglycoside
Cause code misreading in 30s
Only Gram - bugs - Metronidazole
-
Prodrug --> activated by susceptible organism
Protozoa (Giardia)
Anaerobes (C dif, H pylori)
.. Don\'t take with EtOH - Nitrofurantoin
-
DNA Damaging prodrug
..used to prophylactically decrease lower UTI frequency - Diazepam
-
(Valium)
Relaxes striated sphincter to promote bladder emptying
GABA - Dantrolene
-
Relaxes striated sphincter to promote bladder emptying
Blocks Ca2+ release from SR
Can tx malignant hypothermia - Baclofen
-
Relaxes striated sphincter to promote bladder emptying
Works at spinal cord against GABAb receptors - Bethanechol
-
mAChR agonist (similar to AChE inhibitor)
Contraction of detrusor
Increases bladder emptying during atony - Terazosin
-
alpha1 antagonist
decreases urethral resistance
(used for bladder atony/overflow incontinence)
Improves symptoms and flow rate of BPH
Side effects - orthostatic hypotension - Oxybutynin
-
Anticholinergic
Decreases detrusor contractions (tx of storage failure.. to decrease urgency) - Tolterodine
-
Anticholinergic
Decreases detrusor contractions (tx of storage failure.. to decrease urgency) - Finasteride
-
5-alpha-reductase inhibitor
- prevent conversion of T --> DHT
Tx of BPH, urinary retention - Dutasteride
-
5-alpha-reductase inhibitor
- prevent conversion of T --> DHT
Tx of BPH, urinary retention - probenicide
- inhibits the post-secractory reabsorption of uric acid.. therfore increasing renal elimination of uric acid
- Rifampin
- induces p-glycoprotein efflux pump via p450... therefore increases secretion of drugs
- Inhibits efflux pump
- quinidine, verapamil, itraconazole, erythromycin