Ads GI drugs
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- Maalox and Tums
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Ca Co3
bloating and belching - Antacids AE and indications
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can block bioavailability of other drugs
dudenal ulcers GERD prophlaxis for stress ulcers - MOM
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MHOH
antacid
can cause diarrhea - H2 receptor antagonsits
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Zapt and DINE on food
Zantac=ranitidine
Axid=nizatidine
Pepcid=famotidine
Tagamet=cimetidine - Proton pump inhibitors
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Pedro the Li on
blocks H+K+/ATPaseirreversible
Pantoprazole (prevacid)
emeprazole (nexium)
raberprazole
omeprazole (prilosec)
lanzoprazole -
protective mucosal barrier
(sulfated polysaccharides) -
carafate (sucralfate)
forms viscous adherent gel that binds to ulcer craters - prostaglandin analogue
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misoprostol
inhibits gastric acid production
***prevention of gastric ulcer sin patients requiring long terms NSAIDS - serotonin 5HT receptor modulation
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metoclopramide
***accelerates empying of the gut
- worse AE of 5HT receptor modulator
- irreversible extrapyradminla effects
- serotonin antagonist
- ondansetron (Zofran)
- Dompamine antagonists
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compazine
better at motion sickness than Zofran because antihistamone and anticholinergic - antihistamine for GI
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phenergan (promethazine)
diphehydramine
***H1 receptor antagonsit - anticholinergic for GI
- scopalamine
- bismuth subsalicylate is anti
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antidiarheal
anti inflammatory
anti microbial
anti secretory - anti motility and antisecretory agents
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Immodium AD (loperamide)***40 -50 x more potent than morphine
Lomotil - stool softener
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docustate sodium
reduces surface tension of stool allowing water and fats to penetrate