STEP 1: Viruses
Terms
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- DS RNA virus
- Reoviridae
- Diplois viruses
- retroviruses
- ssDNA virus
- Parvovirus
- Oral / Genital lesions
- HSV 1
- VZV
- HHV3, Chickenpox, zoster, shingles
- Hepadnavirus
- Hepatitis B Virus
- RBC Destruction in Fetus --> Hyrops Fetalis
- Parvo B19
-
Small pox
Molluscum Contagiosum - Poxvirus
- Remains dormant in Trigeminal and dorsal root ganglia
- VZV
-
Roseola:
High fevers (seizure) --> Macular rash - HHV 6
-
Test for HSV: ____
Look for ____ -
Tzanck test
Multinucleated Giant Cells -
infects B cells
Think pharyngitis and hepatosplenomegal - EBV
-
Positive Monospot Test
Atypical Lymphocytes
15-20yo - EBV
- MOst common of TORCH infections
- CMV
- 5 picornaviruses
-
PERCH
Polio
Echo
Rhino
Coxsackie
HAV - Hand, Foot, and Mouth disease
-
Coxsackie
"That cock bit me on the hand, foot, and mouth!" - Rabies
- Rhabdovirus
- Councilman Bodies in Liver + Black vomit
- Yellow Fever = flavivirus
- Most common GLOBAL cause of infantile gastroenteritis
- Rotavirus
-
Influenza Viruses
Contain ____ for _____
and _____ for _____ -
Orthomyxoviruses
hemagluttinin for cell entry
neuramidase for virion release
-
BOAR is segemented
This allows for ______. -
BOAR
Bunya (encephalitis, hemorrhagic fever)
Orthomyxo (influenza)
Arena (LCMV)
Rhabdo (Rabies)
reassortment and antigenic shifts - Measles Viruses (2)
-
Rubella
Part of TORCH
Causes fine truncal rash
German 3 day measles
Rubeola
Koplick spots on buccal mucosa
Rash from head to toe -
Bullet shaped
Negri bodies
Long incubation -
Rabies (Rhabdo)
Negri bodies = cytoplasmic inclusions in neurons
Remember that this travels in retrograde fashion up axons
- Break bone fever (dengue fever)
-
Flaviviruses
Arbovirus (transmitted by arthropod) - Oral hairy leukoplakia in AIDS pt
- EBV
-
TORCHES
-
1. Toxo gondii
2. Rubella
3. CMV
4. HIV
5. Herpes simplex
6. Syphillis -
infant with
1. PDA (patent ductus art)
2. Cataracts
3. Deafness -
Rubella
Mother will have lymphadenopathy, arthritis, mabe a rash, and will probably be an immigrant - Blueberry muffin baby
- Rubella
-
Infant with notched teeth and saber shins
Poss hydrops Fetalis -
Syphillis
most will be stillborn - Infant with hearing loss and SEIZURES
-
CMV
only other clue may be that mother had flu-like symptoms and lethargy (mono-like) -
Rash:
Lesions of DIFFERENT AGES - Pox = VZV
- Big Testes, big parotids, meningitis
- Mumps (paramyxo virus)
-
Fitz-Hugh Curtis Syndrome
1. What is it?
2. Causal infections -
1. infection of liver capsule causing adhesions between liver and peritoneum
2. C. Trachomatis (chlamydia)
N Gonorrhoeae -
respiratory therapy eqiupment / prolonged intubation
Common causal infection -
Pseudo. Aeruginosum
(also think burn victims) - AIDS pt with superficial vascular proliferation
- Bartonella Henslae
- AIDS pt with Meningitis with narrow based budding in India ink
- Cryptococcus Neoformans
- AIDS pt with ring enhancing lesions
- Toxoplasmosis gondii
-
Rash, head down, immigrant child (no immunizations)
1. with POSTAURICULAR lymphadenopathy
2. with Cough, Coryza, Conjuctivitis, and Koplick spots -
1. Rubella
2. Rubeola (measles)