STEP 1 Micro: G

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Staph Aureus Lab results: Coag +
Catalase +
Staph Aureus Toxin Mediated Dx (3): 1. Toxic Shock Syndrome
TSST-1 Toxin
2. Scalded Skin Syn
Exfoliative toxin
3. Rapid Onset Food Poisoning
Enterotoxins- Preformed thus speed
Describe Staph Aureus TSST: Superantigen
Binds MHC II and T cell receptor -->
polyclonal T cell activation
Staph Aureus Systems Affected (4): 1. Cardiovascular: Acute bact endocarditis
2. Bone: Osteomyelitis
3. GI: Food poisoning
4. Skin: scalded skin syndrome/ abscess
Staph Epidermidis 1. Lab Results 2. Known for infecting _____: 1. Catalase +, Coag -, Novobiocin Sens
2. Prosthetic devices / catheters
Think Endocarditis
Strep Pneumo 1. Lab results 2. Most Common Cause of ______: 1. Capsule, Catalase -, a hemolytic, Optochin sens bile soluble
2. MOPS
Meningitis
Otitis Media
Pneumonia
Sinusitis
Viridans Strep (S Mutans) 1. Lab Results 2. Think _______ and _______ endocarditis: 1. No Capsule, Catalase -, a hemolytic, optochin resis, NOT bile sol
2. Dental caries (normal mouth flora), subacute
Strep Pyogenes (Group A Strep) Lab Results: Catalase -
b hemolytic
Bacitracin Sens
Strep Pyogenes 3 types of infections: 1. Pyogenic _________ 2. Toxigenic ________ 3. Immunologic _______: 1. Pharyngitis, cellulitis, impetigo
2. Scarlet Fever, Toxic Shock Syndrome
3. Rheumatic fever, acute glomerulonephritis
Scarlet Fever Caused by _____: Strep Pyogenes
Toxigenic
Strep Agalactiae (Group B) 1. Lab results 2. Causes ____, ____, and ____ in _____(age group).: 1. Catalase - , b Hemolytic, Bacitracin Resis,
2. Pnuemonia, sepsis, and meningitis in babies
Enterococci (Group D) 1. ____ Resistant 2. Cause ____ and _____ 3. Where do they live?: 1. Penicillin G
2. Subacute endocaditis, UTI
3. Normal Colonic flora
Strep Bovis (Group D) Cause ____ and _____ in _____ patients: Bacteremia, Subacute Endocarditis
COLON CANCER

* If vignette has colon cancer + infection think Bovis
Diptheria Has a potent ___ that inhibits _____.: Exotoxin
protein synthesis via ADP ribosylation of EF2
Diptheria 1. Main disease process / symptom 2. Described by these 2 things (in vignette): 1. Pseudomembranous Pahryngitis
2. 1)Grayish White membrane
2) lymphadenopathy

*** DO NOT scrape membrane
Diptheria _____ vaccine: Toxoid

Exotoxin is encoded by a b-prophage
Spores: Have _____ in core: Dipicolonic acid
Name the 4 Clostridia w exotoxins 3 descrpitive points on all of them:: 1. Tetani
2. Botulinum
3. Perfringens
4. Difficile

G+BACILLI, Spore Formers, Obligate anaerobes
4 Clostridia w symptom and toxin mode of action: 1. Tetani: spastic Paralysis
blocks Glycine release
2. Botulinum: Flaccid Parlysis
inihibits ACh release
3. Perfringens: Gas Gangrene
a toxin (lecithinase= phospholipase) causes necrosis and hemolysis
4. Difficile: Pseudomembranous Colitis
kills enterocytes
Honey and Babies with paralysis: C Botulinum
Older individual in hospital on broad spectrum antibiotics develops diarrhea Treat with:: C Difficile

Metronidazole
Bacillus Anthracis Gram ___ Only bacterium with ____ capsule that contains _____: 1. +
2. polypeptide, D Glutamate
Listeria Monocytogenes known for: 1. 2. 3. only G+ with ___: 1. Cheese and Deli meat
2. Actin rockets
3. ENDOtoxin
Listeria Monocytogenes Worry about _____ (target population): Pregnant women

Can cause spontaneous abortion and infant/ neonatal sepsis/ meningitis
2 G+ rods that look like Fungi: 1. Actinomyces
2. Nocardia
Toxic shock involves: 1. Symptoms 2. 2 cell types: 1. Fever, vomitting, diarrhea, muscle pain --> severe hypotension and organ failure
2. Tcells and Macrophages

T Cells release IL-2 and activate macrophages , which release TNF and IL1
Non lactose fermenting Indwelling catheter: Pseudomonas Aeruginosa
South American with difficulty swallowing =____: Trypanasoma Cruzi
Chagas Dx: 1. Organism 2. = _____ 3. Destroys ____: 1. T Cruzi
2. Trypanosomiasis
3. myenteric nerve plexuses

Think megacolon or achalasia
Draining ulcers + painful inguinal NODES + red eyes = ______: Chlamydia
Raised, beefy red lesions - not common in the US: Donavanosis
Calammatobacterium Inguinale
______ blocks phagocytosis and the activation of compliment in Strep ____.: Protein M in Strep Pyogenes
_____ lyses RBCs and is produced by Strep _____: Streptolysin O is produced by most strep Pyogenes
______ is used pharmocologically as a thrombolytic agent. It does so by _______.: Streptokinase
It catalyzes plasminogen to plasmin
____ limits herpetic frequency, ____ limits herpetic outbreak shedding and longevity.: VALacyclovir
Acyclovir
Blisters on a child that break and form a yellow crust = ______. If improperly treated, it can then affect the __(organ)___ and cause ____(symptoms)___.: Strep Pyogenes (or Staph Aureus)

Can affect kidney (Post streptococcal glomerulonephritis)

Get Facial edema and dark urine
G- sepsis and toxic shock is caused by the ____ portion of ___.: Lipid A within LPS.
whitish yellow membrane-like plaques = ______ It can proceed to become ____: C. Diff
Membranous Colitis

C Diff is going to be opportunistic - vignette is usually a pt in the hospital being treated with antibiotics for something else
group A strep Think _____ hemolytic, ____ sensitive, and strep _____.: Beta
Bacitracin
pyogenes
comma shaped Will have mucus-y stool: Vibrio Cholera
UTI in sexually active young woman: S Saprophyticus

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Deck Info

Number of cards 41

Created By evrigsby