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Glossary of micro bio hx

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oliver wendell holmes
1840: first contagious fever
ignaz semmelweis
1861, hygeine in hospital to control fever
lister
1870, disinfection/antiseptic, isolated agent
Pasteur
1870, heat inactivation of microbes, discovered pathogens, devpt broth culture, developed attenuated vaccines
Leeuwenhoek
light microscope 1650
Koch
culture media/agar, postulates:
1. org in diseased animal
2. org isolated and grown in culture
3. org reproduces disease when re-inoculated
4. org. re-isolated from infected animal
Jenner
late 1700 rediscovered variolization based on milkmaids/cowpox
metchnikoff
1880s, cell immunity
Ehrlich
1900s, magic bullets with antitoxin/antiserum to treat infection
Florey/Chain
built on Flemming's Penicillin discovery

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