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Glossary of lymphomas and leukemias

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What are the chronic leukemias associated with T-lymphoblasts?
Sezary Syndrome, CLL-T (both L2)
What are the acute leukemias associated with T-lymphoblasts?
ALL-T (L2), ALL-null (L1), ALL-common(L1)
What are the chronic leukemias associated with B-lymphoblasts?
CLL-B (L3)
What are the acute leukemias associated with B-lymphoblasts?
ALL-B (L3)
What are the chronic leukemias associated with monoblasts?
Chonic monocytic (M5), chronic myelomonocytic (M4)
What are the acute leukemias associated with monoblasts?
Acute monocytic (M5), acute myelomonocytic (M5)
What are the chronic leukemias associated with myeloblasts?
CML (M1, 2 and 3), Polycythemia rubra vera (M1), myelofibrosis (M1)
What are the acute leukemias associated with myeloblasts?
AML (M2 and M1), Promyelocytic (M1)
What are the chronic leukemias associated with eos-myeloblasts?
Eosinophilic (rare)
What are the chronic leukemias associated with normoblasts?
Chronic erythroid (M6, rare)
What are the acute leukemias associated with normoblasts?
acute erythroleukemia (M6)
What are the chronic leukemias associated with megakaryoblasts?
Idiopathic thrombocytopenia (M7)
What are the acute leukemias associated wwith megakaryoblasts?
acute megakaryocytic leukemias (M7)
What type of cell proliferates in MM, and what is its histologic appearance
Monoclonal plasma cell, fried egg appearance
Where does MM arise?
bone marrow
The 2 most common ab's, in order, are:
IgG (55%), IgA (25%)
Common multiple myeloma symptoms are:
lytic bone lesions and hypercalcemia, renal insifficiency, increased suscpetibility to infection, anemia
This disease is associated with:
primary amyloidosis
Ig light chains are also called:
Bence Jones proteins
3 key diagnostic features:
lytic bone lesions on x-ray, M-spike on serum protein electrophoresis, Bence-Jones proteins in urine
Red blood cell appearance on peripheral smear:
Rouleaux formation (poker chips)
What 2 differences are seen in Waldenstrom's macroglobulinemia?
M-spike is IgM, no lytic lesions

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