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Glossary of Virology3

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In general what 3 roles does a lab play in viral testing?
1. Diagnosis
2. Determining immune status
3. Assess patient prognosis
What are the 5 categories of viral testing methods in labs?
1. Cell culture
2. Serology
3. Histology
4. Cytology
5. Molecular methods
Let's talk about hepatitis
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What disease is Hepatitis B and some C associated with?
Hepatocellular carcinoma
Which hepatitis viruses are chronic?
B, C, and D
Which are acute?
A and E
What is the agent structure of Hepatitis A?
Icosahedral capsid, ssRNA
What is the agent structure of Hepatitis B?
Enveloped dsDNA
What is the agent structure of Hepatitis C?
Enveloped ssRNA
What is the agent structure of Hepatitis D?
Enveloped ssRNA
What is the agent structure of Hepatitis E?
Unenveloped ssRNA
What is the agent structure of Hepatitis G?
ssRNA
Which hepatitis viruses are transmitted parenterally, through close contact?
B, C, D, G
How is Hep A transmitted?
fecal-oral
How is Hep E transmitted?
Water-borne
Which hepatitis viruses can enter a carrier state?
B, C, D, and G.
What serologic test has the best sensitivity for hepatitis viruses?
EIA
What causes an infected individual to enter a carrier state?
Immunosuppression during the active infection.

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