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Strep

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How do we differentiate Sterp from Staph in the lab
Catalase Neg
On Blood Agar what three results can you get
Alpha - partial hemolysis green
Beta - clear colonies
Gamma - no hemolosys
What Strep are Alpha Hemolytic
S Pneumo - + Quellung Optochin Sens.
S Viridans - No Capsule - Optochin Resis.
What Strep are Beta Hemolytic
GAS - Bacitracin Sens
GBS - Bacitracin Res
What are gamma Hemolytic
Enterococcus
What are Lancefield antigens
Classification of the C antigen of Carb in the cell wall
What dz does GAS cause (6)
Pharyngitis, cellulitis, Scarlet Fever, Strep TSS, RF, PSGN
Antigenic Markers fo GAS
C Carb
M Protein - Antigenic, Protect from complement, Phago, site of antibody opsonization
GAS Enzymes (4)
Streptolysin O
Streptolysin S - O2 Sens.
Pyrogenic Exotoxin - Scarlet fever
Others - Steptokinas DNAse Hyalurinidase
Sptreptolysin O (4)
O2 Labile
Causes Beta Hemolysis
Antigenic
Anti-ASO antibodies Dx
Pharyngitis Features (4)
Erythematous Tonsils
Purulent Exudate
Temp
LN
Skin INfections of GAS (4)
Folliculitis
Cellulitis
Impetigo
Necrotizing Fascitis
Sx - Redness, swelling, warmth, and pain of Skin
Si - Inflammation of the connective tissue underlying the skin
Hx - cut
Celulitis
Fever Pain Sweling over area
Swelling, Bronzing, Hemorrhagiv Bulla
Necrosis in Dermis and Subcut fat
Necrotizing Fasciitis
Rheumatic Fever (5)
Chorea
Myocariditis
Rash
Nodules
Polyarthiris

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