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Glossary of Rubella

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What are 4 main effects of the Rubella virus?
1. Vasculopathy
2. Inhibition of Mitosis
3. Chromosomal breakage.
3. Infarcts
-VICI-
What is the classic triad of congenital rubella?
1. Heart deformity
2. Cataracts
3. Deafness
Is there a treatment for rubella?
No
What population is targeted with the rubella vaccine?
Child-bearing age/college students
How is rubella not diagnosed?
Cell culture - it produces no CPE.
How IS rubella diagnosed?
Via the production of interferon in a culture media after secondary exposure to the virus.
What type of virus is the rubella virus?
Enveloped ssRNA virus
What happens after a primary infection with rubella?
Protection for LIFE!
What symptoms are seen in a rubella RE-infection?
-Scanty virus excretion from throat for 1-4 days.
-Rise in IgG titer
What symptoms are seen in PRIMARY rubell infectiona?
Rash, Virus excr 1-3 days, viremia, transplacent. passage, IgG AND IgM antibodies.
Are the symptoms from a rubella vaccine more like primary or secondary infections?
PRimary
How are vaccine symptoms NOT like primary infection?
-Shorter incubation (7-10 days inst. of 14-21)
-Rarely a rash

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