Respiration Quiz II
Terms
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- Partial Pressure of oxygen
- PO2= Pb x Fo2= barometric pressure x fractional component of oxygen
- What causes right shift of oxygen-hemoglobin dissociation curve?
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Increased: CO2, temp, 2,3-DPG
Decreased: pH - What causes left shift of oxygen-hemoglobin dissociation curve?
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Increased: pH
Decreased: CO2, temp, 2,3-DPG - Central Chemoreceptors
- decrease in pH of brain ECF
- Peripheral chemoreceptors
- decrease in arterial PO2
- Stretch Receptors
- stretch of lungs during inflation
- Irritant Receptors
- alergen,lung inflammation, histamines
- Pulmonary C Fibers
- interstitial pulmonary edema
- Nasal, Laryngeal, and Pharyngeal Receptors
- mechanical and chemical irritants
- Jonint and Muscle Receptors
- Limb Movement
- No ventilation
- Decrease in V/Q to 0
- Normal
- V/Q is about 1
- No Perfusion
- Increase in V/Q to infinity
- Bohr Effect
- When pH of blood decrease, there is a decrease in the affinity of hemoglobin for oxygen-> release of oxygen
- Haldane Effect
- When the pH of blood increases, there is a decrease in the affinity of hemoglobin for carbon dioxide
- Medullary Respiratory Centers
- Brainstem- generate basic rhythmic pattern
- Pontine Resp. Cntrs
- Brainstem-pneumotaxic and apneustic centers
- Pneumotaxic Center
- switch off the inspiratory neurons
- Apneustic Center
- Prevent inspiratory nerons from being switched off
- one
- modifies the activity of brainstem neurons-alters breathing
- Zone 1
- PA>Pa>Pv -> no blood flow-ventilated, not perfused
- Zone 2
- Pa>PA>Pv -> as pressure difference increases toward bottom, blood flow will increase
- Zone 3
- Pa>Pv>PA -> capillaries are permentently opened