Pharm Exam 1: Analgesics
Terms
undefined, object
copy deck
- Chemical Classes of Opioids
-
1. meperidine
2. methadone
3. morphine
(-like agents) - Meperidine- like Agents
- meperidine, fentalnyl, remifentanil, sufentanil, alfentanil
- Methadone- like Agents
- methadone and propoxyphene
- Morphine- like Agents
- morphine, heroine, hydromorphone, oxymorphone, levorphanol, codeine, hydrocodone, oxycodone
- 5 opioid receptors
- mu, kappa, sigma, delta, and epsilon
- Common Opioid Side Effects
- respiratory depression, constipation, urinary retention
- Cough suppressant
- codeine, hydrocodone
- Anti- diarrheal preparations
- paregoric, Lomotil
- Agonist for mu
- morphine, produces supraspinal analgesia, respiratory depression, ++sedation, euphoria
- Agonist for kappa
- ketocyclazocine, produces spinal analgesia, ++++ sedation, miosis
- Agonist for delta
- enkephalins, produces analgesia
- Cardiovascular side effects for opioids
- Palpatations, hypotension, flushing
- CNS effects for opioids
- sedation, disorientation, euphoria, lightheadedness, dysphoria, lower sezizure threshold, tremors
- GI effects for opioids
- nausea, vomiting, constipation, biliary tract spasm
- Integumentary effects for opioids
- rash, itching, wheal formation