Glossary of Pathogenicities
Other Decks By This User
- Staphylococcus epidermidis
- ubiquitous on skin/mucous membranes;
1. Bacterial endocarditis involving prosthetic valve (extracell. slime)
2. Surgical prostethesis infection
- Staphylococcus saprophyticus
- -Not normal flora
-UTI in sexually active 18-25 yr old females
- Staphylococcus aureus
- normal flora in skin/mucous membranes;
A. Diseases of skin
2. Boils, furuncles
6. Scalded Skin Syndrome (ritters dis)
B. Diseases of Digestive tract - food poisoning
C. Post-op/wound infections
E. TSS-toxic shock
G. bactermia, endocarditis, meningitis, UTI, stye.
- 6 extracellular substances --> mechanisms for S. aureus disease
- 1. Exfoliative toxin
C. enterotoxin (exotoxin, heat-stabile)
E. protein A
f. others - very virulent
- S. aureus food poisoning
- 2-6 hr incubation
unrefrigerated hi-protein food ingestion
nausea, vomit, diarrhea
self-limiting in 24 hrs
cause: enterotoxins A and D
- #1 cause of osteomyelitis
- Staph aureus
- Cause/symptoms of TSS
- -Staph aureus TSST-1 exotoxin
Inital - hi fever, dizzy, vomit, diarrh.
48 hrs - sunburn rash, hypotensive
- Streptococcus viridans
- Normal flora in mouth/vagina
Subacute Bacterial Endocarditis in damaged (not prosthetic) heart valve (from Rheumatic fever)
- Normal flora in intestine
- Strep group D non-enterococcus
- Normal flora in wait it's RARE in humans
- S. pneumoniae
- normal flora in oral cavity (small #)
Pathogen because of capsule
1. Lobar pneumonia
3. Otitis media
- Pathology/symptoms of pneumonia
- GPdC S. pneumonia enter lungs; Lobar consolidation from immune response.
High fever, shaking chills, sharp pleural pain, rusty sputum
- Strep group A --> S. pyogenes
- normal flora in oral cavity of some
1. Strep throat
2. Scarlet fever
3. Erysipelas, cellulitis
5. Wound infections
6. Pyogenic infections
Necrotizing fasciitis, TSS-like
7. Post-strep diseases (Acute glomerulonephritis, rheumatic fever)
- 5 Extracellular products causing Strep pyogenes (groupA) diseases:
- Streptokinase - breaks fibrin, spreads
Streptodornase - degrades DNA of host
Hyaluronidase - degrades connect. tissue
Erythrogenic toxin -scarlet fever color
Hemolysins O and S
- symptoms of strep throat
symptoms of scarlet fever
- pharyngitis, pyogenous tonsils, slight fever, cervical lymphadenopathy
strep throat + red rash from erythrogenic toxin
- 2 pyogenic Strep A infections:
- necrotizing fasciitis - flesh eating
toxic shock-like syndrome
- 2 post-strep diseases
- 1. acute glomerulonephritis
2. rheumatic fever
both are hypersensitive reactions from prior infection. seen app. 3 wks after initial infection.
- Who does Strep group B (agalactiae) typically cause infections in?
Normal flora in:
-Oral cavity in low #s. May colonize vagina but not normal.
- #1 cause of neonatal meningitis and sepsis:
- Strep group B agalactiae
- Infections caused by Strep group B:
- Neonatal Meningitis/Sepsis
Neonatal Respiratory Distress Syndrome (RDS)
- B-hemolytic STreps not A, B, or D:
normal flora in:
- Oral cavity
- What gram positive catalase neg cocci is intrinsically resistant to Vancomycin?
- Neisseria gonorrhoeae causes what infections?
By what four virulence factors?
- Gonorrhea, Gonococcal pharyngitis, neonatal ophthalmia
-IgA protease (inhibits IgA)
- symptoms of gonorrhoea:
- Males: urethritis, dysuria, purulent dischare.
Females: cervicitis, vaginitis, itching/discharge or asymptomatic.
- Gonorrhoea complications:
- PID (pelvic inflammatory disease)
- Neisseria meningitidis causes what disease?
- Saprophytic neisseria commonly normal flora in:
- Mouth --> IN EVERY MOUTH CAVITY
- What diseases does Moraxella catarrhalis cause?
- Otitis media, sinusitis, pneumonia, meningitis.
- What infection is caused by Corynebacterium diphtheriae?
What causes the pathogenicity?
Lysogenic phage encoding exotoxin invades the bacteria; causes production.
Pharyngeal membrane, edema, fever, Bull's neck, lymphadenopathy.
- Where are the Diphtheroids normal flora, what type of infection could they cause
which one is most common
- skin, mucous membranes, vagina.
SBE, bacteremia. only opportunistic in susceptible people though.
Most commonly would be C. jeikeium.
- Which Corynebacterium causes encrusted cystitis?
- C. urealyticum - produces urease and an NH3 around itself protecting itself from phagocytosis. Chronic UTI
- Type of infection caused by Listeria monocytogenes
- Foodborne illness (from cold packaged hot dogs, cheese, milk)
Septicemia/Meningitis in Neonates and susceptible adults.
- What does Erysipelothrix rhusiopathiae usually cause
- Erysipeloid (localized cellulitis)
zoonotic disease from hogs to butcher or vet
- 2 types of Bacillus cause what three types of disease?
- B. anthracis - anthrax
B. cereus - diahhretic or emetic food poisoning
- 3 variations of Anthrax:
- -Cutaneous (forms black eschers)
- Difference between emetic and diarrhetic food poisoning:
- emetic is shorter 1-6 hr incubation
comes from fried rice
diarrhetic is longer 6-24 hr incubation
comes from meats/sauces
- Infections by Haemophilus influenzae:
- Respitory: Pneumonia, sinusitis, otitis media.
Meningitis in infants under 2 yrs old
- What infections would Haemophilus non-influenz. cause (hemolyticus, parainfluenzae, parahemolyticus, etc)?
Where normal flora
- In suscp. patients, Bacteremia or SBE
normal in oral cavity
- what does haemophilus ducreyi cause?
- chancroid; painful ulcers, inguinal lymphadenopathy
- What bacteria causes whooping cough?
- Bordatella pertussis
- what does bordetella bronchiseptica cause
- respitory tract infections (pneumonia)
- what is especially frightening about Listeria monocytogenes?
- If acquired during pregnancy, can cross the placenta and cause stillborn birth in a neonate.
or cause fetal infections of septicemia and meningitis.
You must Login or Register to add cards