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Glossary of Neuro mass differentials from AFIP

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Location

Differential
CPA cistern (extra-axial)

* Vestibular Schwannoma
* Meningioma
* Epidermoid (no enhancement, undulating margin)

* Glomus Tumor, Mets, Endolymphatic Sac Tumor
* Extension from 4th or Primary CPP and Ependymoma

Location

Differential
4th Vent / Vermian Mass

* PNET (medulloblast) - usu DENSE on NCT
* Ependymoma - usu MIXED w/Ca &small "cysts"
* Choroid Plexus Papilloma (adults)

Location

Differential
Hemispheric Cerebellar Mass/ Cyst+Nodule

* Pilocytic Astrocytoma (5-15 yrs)
* Hemangioblastoma (35-45 yrs)
* Other Hemispheric Masses:
-Mets, Infarction, Abscess

Location
& differential
Sella & Parasellar / Suprasellar

* Pituitary Adenoma (adults)
* Craniopharyngioma
* Hypothalamic Glioma (kids)
* Chordoma, Meningioma, Mets
* Histiocytosis, Germinoma, Lymphoma, Sarcoid
* Aneurysm

Location &
differential
3rd Ventricle

* Colloid Cyst
* CPP, Ependymoma
* Vertical Ext Suprasellar Mass
* Anterior Ext of Pineal Mass
* Cysticercosis

Location
& differential
Basal Ganglia

Bilat Symmetric (tox/metab)
* Putamen - Methanol
* Globus Pallidus - CO
* Genetic Disorders
Bilateral Asymmetric (hematog)
* Infection (Toxo, etc.)
* Metastasis
Unilat (acquired/neoplastic):
* Thalamic Glioma (astrocyt)
* Hypertensive Hematoma (Dx of exclusion)

Differentials
for each location
Lateral Ventricle

* F. Monro
o SEGA
o Subependymoma
* Body
o Subependymoma, etc.
* Trigone
o Child - CPP
o Adult - Meningioma

Location
and differential
Pineal Region (Quadrigeminal Cistern)
* Pineal Parenchyma
o Pineocytoma, Pineoblastoma
* Pineal Cyst (=CSF on T1&2; hi FLAIR)
* Germ Cell Tumor -
o "atypical teratoma"
* Extension of Glioma (Astrocytoma)
o corp call, tectum, thalamus
* Meningioma
* Lipoma
* Vein of Galen Malformation
* Epidermoid

Location

& differential
Corpus Callosum

Expanding or Enhancing
- Astrocytoma, Lymphoma

Destructive, Geographic
- WM Dz- MS, ADEM, PML

Patchy Periventricular
- Vascular: HT change, leukoariosis)
- Multifocal rings - Toxo in HIV

Uniform Periventricular
- Hydrocephalic edema

Differential
------GM Ribbon------
-Ischemia (+/-Infarct)
-HTN Encephalopathy, Eclampsia
-Cyclosporin
-Encephalitis (HSV), Meningitis
-Sturge-Weber Disease (Ca++)
-Meningioangiomatosis (Ca++)
-----Gray & White Wedge-----
-Infarct (vasc territory)
-Cortical Dysplasia
-Cortical Tuber (TS)
-DNET (LoT1 HiT2, no edema)
rare: Gangioglioma (cystic w/Ca++)

Location
& Differential
Epidural Space

* Hematoma
* Empyema
* Mets (Prostate, Breast, Lymphoma)
* Granulomatous dz(e.g. Sarcoid, TB, Fungal)

Location
&
differential
Subdural Space

* Hematoma
* Empyema
* Mets (Prostate, Breast, Lymphoma)
* Granulomatous Dz (Sarcoid, TB, Fungal)

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