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Glossary of NUTR 110 - Lipoprotein types and enzymes

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activated by apoCII
Liporpotein lipase (LPL)
protein that exchanges TG and CE betwteen HDL, VLDL, LDL
cholesterol ester transfer protein (CETP)
hydrolyzes TG from chylos and VLDL to FA and glycerol
Liporotein lipase (LPL)
enzyme that hydrolyzes unsaturated FA from lipoprotein
Lecithin cholesterol acyl transferase (LCAT)
Secreted by muscle (heart skeletal) and
adipose cells
lipoprotein lipase (LPL)
Chylo after much TG has been removed by LPL
chylomicron remnant
Binds to receptors (LDLR and LRP) present on liver cells
chylomicron remnant
lipoprotein synthesized by intestinal mucosal cells
chylomicron
transfers dietary TG and fat soluble vitamins through lymph to thoracic duct of heart
chylomicron
Gone from serum 8-12 hours after a fatty meal
chylomicron
synthesized by liver
VLDL
transports TG to muscle and adipose
VLDL
Its TG component hydrolyzed by LPL
VLDL
remnants of VLDL with much TG removed and with CE added (from HDL)
ILD (intermediate density lipoprotein
TG depleted VLDL
LDL
carries cholesterol ester
LDL
binds to LDL receptor via apoB100
LDL
2/3 removed by liver
LDL
after endocytosis, CE released into cell lysosome
LDL
half life 2-3 days, thus transports most cholesterol in blood
LDL
After oxidation, removed via scavenger pathway in macrophages
LDL
scavenges free cholesterol from membranes
HDL
Its cholesterol is esterfied (with FA from PC) by LCAT
HDL
CEPT exchanges TG and CE between WHAT and VLDL, LDL.
HDL
carrier for extra A, C and E apoproteins in blood
HDL
Attached to endothelial cells that line capillary blood vessels of muscle and adipose tissue
lipoprotein lipase (LPL)

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