Glossary of N224 Pathophysiology - Exam 3 - MSU - Huether chapters 19,20
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- Name the 6 TYPES of hematologic alterations. (According to the professor)
- Erythrocyte fx
Myeloproliferative RBC disorders
Platelets and coagulation
- Define Anemia
- the reduction in total # of erythrocytes or the decrease in quantity or quality of hemoglobin
- Name the 3 main causes of Anemia
- altered production of e-cytes
increased destruction of e-cytes
- Normocytic, macrocytic and microcytic refer to what re: anemia?
- the erythrocyte volume (size)
- normochromic, hypochromic refer to what re: anemia?
- the Hemoglobin content
- What does pernicious mean (physiologically speaking)?
- B12 defieciency
- According to professor, what are the 3 types of anemia.
normocytic-normochromic (least common)
- Describe the differences in manifestation between B12 deficiency and Folate deficiency
- Folate deficiency manifests the same as B12 deficiency except for the neurological symptoms.
(weakness, paresthesias of feet and fingers, difficulty walking)
- How fast do macrocytic-normochromic anemias develop?
- Slowly, over 20-30 years.
- What physiological activity does the B12 or folate deficiency directly affect, which in turn affects the e-cyte synthesis
- RNA and DNA synthesis
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