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Glossary of Microbial Mechanisms of Pathogenicity

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1. List the four "musts" for a bacterium to cause disease.
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1. What is virulence? What is pathogenicity? How do they differ?
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1. What surface structures do bacteria use to adhere to tissues?
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1. List 5 extracellular enzymes bacteria use to avoid and evade the immune system.
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1. Why are capsules important to a pathogenic bacterium?
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1. How do exotoxins differ from endotoxins?
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1. List some properties of exotoxins.
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1. What is a toxoid? An antitoxin?
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1. What type of toxins are the botulinum toxin? The cholera toxin? The tetanus toxin? That is, what part of the body does each affect?
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1. What is endotoxin? Where is it found on the cell? What bacteria have endotoxin?
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1. What does endotoxin do and how does it do it? Why is endotoxin the virulence factor that it is?
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1. What is endotoxic shock?
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1. Are plasmids important in bacterial virulence? Why or why not? What do they code for that is of interest to pathogenic microbiologists?
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1. What is viral conversion?
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1. How do bacteria cause disease?
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1. How do viruses cause disease?
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