Glossary of Intro to Psych 2

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Epidemiologic Catchment Area (ECA) study and the National Comorbidity Study (NCS) results
30% of adults will have diagnosable mental illness in any given year

50% have one in their lifetime
Leading cause of disability in the world
unipolar depression
depression shortens the life expectancy of MI patients & patients with cancer T/F
Major Depression Occurs concommitantly in
9-31% in patients 3-4 months after stroke
16-30% in patients with multiple sclerosis
20-30% in patients with Parkinson’s disease
T/F depressed patients cost more to treat
Seven Probable Mechanisms Related to Depression and Cardiovascular Disease
Noncompliance with cardiac rehabilitation and medical regimens
Risk factor clustering (e.g., smoking, hyper-tension, diabetes, hypercholesterolemia, obesity)
Hypothalamic-pituitary-adrenal (HPA) axis hyperactivity and cortisol elevation
Decreased heart rate variability
Elevated plasma levels of pro-inflammatory cytokines leading to atherosclerosis
Platelet activation and hypercoagulability
Psychological stress
Persons with bipolar disorder are at higher risk for type II diabetes T/F
Migranes are often diagnosed with depression
Depression is associated with volume changes in the brain T/F
it is unclear whether these changes are due to the depression or the higher instances of comorbid illness
Depression’s Physical Toll
Amygdala hyperactivity
HPA dysregulation resulting, at least in part, from disruption of normal sleep patterns
Delayed atrophy of hippocampus, prefrontal cortex, along with bone mineral loss and abdominal obesity
Increased risk of cardiovascular disease

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