Glossary of ID 6.34
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- a.k.a. Nematodes
Ingest eggs, larvae migrate to lungs
Swallow larvae, adult worms grow in gut
Only problematic if heavily infected - may lead to intestinal obstruction or malnourishment
- Zoonotic ascaris
People ingest eggs, larvae invade but cannot complete their life-cycle
This results in larvae swimming around in blood stream w/no way to get out.
Result? Liver/Brain/Eys dissemination (w/granuloma formation)
- Visceral/Ocular Migral Larvans
- Sequelae of toxocara infection (zoonotic ascaris). Larvae incapable of leaving body and elicit an inflammatory response (granulomas) that can be found w/in viscera or eyes!
- Larvae penetrate skin, migrate to lungs and are swallowed
Adult worms reside w/in gut and munch on villi, dispelling eggs in stool
- Cutaneous Larva Migrans
- Due to zoonotic hookworm infection
Worms cannot migrate to lungs to complete lifecycle
This results in a pruritic, serpentine rash
- Ingest eggs
Larvae mature in lungs
Generally asymptomatic unless heavy infection
- Enterobius Vermiculus
Ingest eggs, larvae mature in gut. Female worm sheds eggs @ night in the perianal area
- Larvae infect skin, migrate to and mature w/in intestinal wall
Adult worms shed larvae in stool
The larvae will REINFECT host via perianal skin
In addition, will often drag additional pathogens (i.e. surface bacteria) with them!
- Which Helminth is implicated in autoinfection?
Pass larve that will reinfect through perianal skin
- Which Helminth is implicated in hyperinfection?
With heightened reinfection, these larvae will drag other pathogens into the body (i.e. surface bacteria). The resulting scenario = sepsis on top of helminth infection
- Eat infected meat (cysts w/larvae)
Larvae become adult worms, which churn out new larvae
Larvae migrate through intestine and take residence in MUSLCE - cause myositis
- Which helminth causes myalgia?
- Tricinella (larvae invade muscle)
- Filarial Parasites
- 1) Lymphatic filiarsis: spread by mosquitos; adult worms reside w/in lymph nodes and cause obstruction (elephantitis)
2) Onchocerciasis: skin/eye lesions - river blindness
3) Lao Lao: continuual migration through soft tissues/eyes
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