Glossary of ID 6.11
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- Pico = Small
(+) (P, for positive) ssRNA
- Think "Little PHK-ER"
- Of Picornaviridae (Little PHK-ERs)
Tells you they're non-enveloped, small, ssRNA
PEECABoo (the types)
Coxsackie, A and B
(Enterovirus, Hepatovirus, Parechovirus)
- Surface cytocidal
Systemic cytocidal (viremia and disseminated infection, organ specific disease)
- Most common cause of acute Aseptic Meningitis?
Symptoms: fever, severe headache, nausea/vomiting, stiff neck, blood "viral pattern" (absent leukocytosis)
- What is a blood viral pattern?
- Normal counts or lymphocytosis
- Major Syndromes attributed to Enterovirus, Hepatovirus and Parechovirus Infection
- Aseptic Meningitis
- Coxsackie B
- Myocardities and Pleurodynia
- Coxsackie A
- Febrile exanthem and herpangina (think rashes all over)
- Febrile Exanthem/Enanthem
- Due to Coxsackie A/ECHO
- Do enteroviruses cause diarrhea?
- Generally, their infection is ASYMPTOMATIC. You MUST KNOW THAT Rotavirus and Enteric Adenoviruses are the leading agents of viral gastroenteritis
- Epidemiology of Enteroviruses
- WARMER MONTHS
- Hepatovirus (Hepatitis A Virus)
- It's a "Little PHK-ER"
Part of the picornaviridae (tells you they're small, non-enveloped, (+) ssRNA)
Fecal-oral route w/systemic spread to Liver (as a systemic infection, tells you that you'll have a long incubation period)
- Hepatitis A Virus
- Fecal-Oral Route
Ingested w/Systemic spread to Liver (long incubation period)
Infection may be asymptomatic, symptomatic (non-icteric or icteric)
- Hepatitis A Virus
- Endemic in all countries
Vaccinations are effective as suggested in high-risk groups in the developed world
- It's a "Little PHKER"
Tells you it's of Picorniviridae (small, (+) ssRNA, and non-enveloped)
Most common cause of the common cold (URI)
- Clinical symptoms of the common cold
- Sneezing, nasal obstruction and discharge
VERY COMMON Infections
TONS of serotypes (so it makes vaccination improbable)
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