Glossary of Hep A
Other Decks By This User
- What is the first serological marker detected in Hep A?
- fecal hepatitis A virus - HAV
- When is Fecal HAV detected?
- during the incubation phase, 15-45 days.
- When does the acute disease of Hep A set in?
- 2-12 weeks
- What Hep A markers show up during the acute disease stage?
- IgM anti-HAV first, then IgG.
- How would you know was in Convalescence and recovery?
- If IgG Anti-HAV was high but IgM was low or not detectable.
- what is the structure of HAV again?
- Icosahedral capsid with ssRNA.
- What is the structure of Hepatitis C virus??
- envelped ssRNA.
- what is theearliest marker in hep C other than serum transaminases?
- HCV-RNA detected.
- When is HCV RNA first detectable, and then peak?
- First is in incubation period.
Peak is during 1-3 wk period of acute disease.
- How would you know a Hepatitis C case was going to resolve?
- Would see IgM and IgG Ant-HCV rise in the mid-late symptom phase.
- What are the signs of chronic hepatitis C?
- Symptoms reappear and disappear.
No anti-HCV ever appears!
HCV-RNA is detectable for months to years, not just first 3 wks.
- What 2 ways does Hep D infect individuals?
- 1. Coinfection w/ Hep B
- What is the difference between coinfection and superinfection?
- Co = Hep D and B infect at the same time.
Super = Hep D infects a person that already has Hep B
- Which is worse, co or super?
- Super. B/c 80% of people with it progress to cirrhosis, where 90% of coinfections recover.
- How can you differentiate serologically a hep D coinfection from super?
- Hep B markers: follow relatively normal course.
Hep D markers: HDV RNA is only present for a while, where it REMAINS in a superinfection. Also, total Anti-HDV drops way off in co-infection, but stays HIGH in super.
You must Login or Register to add cards