Glossary of GI tract infection
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- What are the normal host defenses for the GI tract?
- -Stomach HCl
-Intestinal sIgA, peristalsis, normal flora, phagocytes.
- What are the 3 main ways of acquiring bacterial enteritis?
- 1. Invasion of intestinal mucosa and organism proliferation
2. Colonization of GI tract then exotoxin production.
3. Ingestion of preformed exotoxin
- What 7 organisms can invade the intestinal mucosa and proliferate?
- LESS VEY
- What does less vey stand for?
- Listeria, Enteropathic Ecoli,
- What does shigella cause?
- Bacillary dysentary transmitted fecal to oral.
- How is salmonella passed?
- Which 2 of these organisms produces H2S?
- How is Edwardsiella transmitted?
- By fish and reptiles/aquariums.
- How is Yersinia enterocolitica passed?
- In undercooked milk and pork. May be in blood transfusion bags
- Hey! what's EPEC?
- Enteropathogenic E. coli - causes enteritis, but is less common than hemorrhagic.
- what is vibrio parahemolyticus found in?
- Shellfish and sea food in the far east.
- What does Listeria monocytogenes like and is found in?
- Cold - cheese, dairy, hot dogs.
- What 8 pathogens colonize the intestinal tract then produce exotoxin?
- 1. Hemorrhagic Ecoli
2. Enterotoxigenic Ecoli (ETEC)
3. Vibrio cholerae
4. Campylobacter jejuni
5. Aeromonas and Plesiomonas
6. Clostridium perfringens
7. Clostridium difficile
8. Clostridium botulinium in honey for infants
- Where is Hemorrhagic ecoli found?
- Petting zoos, undercooked beef
- What does Ecoli 0157 H7 cause in kids?
- Hemolytic Uremic Syndrome HUS
- How does ETEC differ from EPEC?
- antigenically; enteropathogenic invades mucosa and proliferates; toxigenic colonizes and produces exotoxin.
-Via contaminated food/H2O
- How is vibrio cholerae transmitted?
- In water.
- What is Campylobacter jejuni transmitted in?
- How do Aeromonas/Plesiomonas diff from most GNB?
-How do they affect stools?
-How are they transmitted?
- -They are oxidase positive
-Turn stools green/malodorous
-In contaminated water
- Where is Clostridium perfringens found?
- In cafeteria food
- What is Clostridium difficile caused by?
- -Antibiotic associated
-Suppression of normal flora
- How must Clostridium diff. be tested for?
- It CANNOT be cultured; must test for Toxins A and B in stools with EIA.
- What causes infant botulism?
- Honey - in infants under 6 mo b/c of lack of normal flora.
- What 4 organisms cause enteritis from ingestion of preformed toxins?
- 1. Staph aureus - protein foods
2. Bacillus cereus - fried rice, meat sauces
3. Clostridium botulinum - canned foods.
- ON TO PERITONITIS
- What are the 2 broad types of peritonitis?
- 1. Primary - no known cause.
2. Secondary - obvious reason
- What 4 organisms are found in Primary peritonitis in kids?
- 1. Strep pneumo
2. Strep A
3. Staph aureus
- What 3 organisms are found in Primary peritonitis in adults?
- 1. E. coli/other enterobacteria
2. Strep pneumo
3. Strep A
- What 4 things cause secondary peritonitis?
- 1. Trauma - surgery, hernia, cancer, perforated bowel.
3. Primary infection elsewhere
4. Peritoneal dialysis -CAPD
- What does CAPD stand for?
- Chronic ambulatory peritoneal dialysis - in end stage renal disease.
- What are the 2 most common enterococci?
which is MORE common?
which is more antibiotic resist?
- -Fecalis - 80-90%
-Faecium - 90% resist vancomycin
- How do you seperate Enterococcus from streps?
- -Bile esculin pos
-6.5% NaCL Pos (alternt is PYR)
- How do you speciate enterococci?
- With Carb fermentation - sorbitol and arabinose
- What are the Sorbitol/Arabinose reactions for:
- Facalis = Sorb + Ara -
Faecium = Sorb - Ara +
- What is Mannitol salt or CNA for?
- Staph aureus/gram pos cocci
- What is BA used for when testing for ENTERIC organisms?
- Better growth for oxidase test with fastidious organisms.
- What is SMAC for?
- Hemorrhagic E. coli
- What is Skirrow media for?
- What are the characteristics of campylobacter?
- -Grows at 42'C for 48 hrs in microaerophilic environment.
-Curve GNB, Oxi +/Catalase +
-Darting umbrella motility
- What is each for:
- TCBS = Vibrio
CIN = YerCINia
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