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Glossary of DMP 715 Path Exam 1 Necropsy

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MD

pancreas, hyperplasia, multifocal

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pancreas, nodular hyperplasia, multifocal

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Liver, nodular hyperplasia nodules hyperplasitc multifocal to coalescing

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liver, cirrhosis, chronic damage end stage liver disease, multifocal to coalescing nodular regeneration and fibrosis, hypertrophy and hyperplasia of hepatocytes

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liver, cirrhosis, chronic damage end stage liver disease, multifocal to coalescing nodular regeneration and fibrosis

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liver, cirrhosis, chronic damage end stage liver disease, multifocal to coalescing nodular regeneration and fibrosis, hyperplasia and hypertrophy of hepatocytes (not flat so not necrosis)

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pectoral muscle, atrophy, (poor nutrition, starvation)

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pectoral muscle, atrophy

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stifle, degenerative joint disease with synovial hyperplasia - fibrosis, (would have had ruptured cruciate for years, caused by instability of joint and physiologic stress)

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prostate, hyperplasia (stimulus testosterone, common in old intact male dogs)

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prostate, hyperplasia bilateral enlargement (stimulus testosterone, common in old, intact male horses)

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prostate, hyperplasia xsec (common in old, intact male dogs, stimulus is testosterone)

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small intestine, mucosal hyperplasia, diffuse (proliferative ilelitis, Lawsonia intracellularis)

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small intestine, mucosal hyperplasia, diffuse (proliferative ilelitis, Lawsonia intracellularis)

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small intestine, mucosal hyperplasia, diffuse (proliferative ilelitis, Lawsonia intracellularis)

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Nostril, loss of dorsal turbinates and atrophy of ventral turbinates (Atrophic rhinitis, Pasteurella multocida - breaks down turbinate structure)

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Nostril, loss of dorsal turbinates and atrophy of ventral turbinates (Atrophic rhinitis, Pasteurella multocida - breaks down turbinate structure)

MD Horse Heart

Heart, necrosis multifocal to coalescing, tan streaks transmurally (across wall) (necrosis could be due to toxin or vitamin E deficiency)

MD Horse Heart

Heart, necrosis multifocal to coalescing, tan streaks transmurally (across wall)

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Spleen, necrosis, multifocal diffuse spots of variable size (cat with Tularemia)

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liver, necrosis, multifocal pale, tan (say how many and size) (fusobacterium necrophorum caused, pale areas on capsular areas and spread through parenchyma)

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placenta: cotyledons, necrosis, multifocal (necretizing placentitis) (Toxoplasma gondi?)

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liver, lipidosis, severe, diffuse (no tan or white spots or streaks) swollen, yellow friable (breaks easily) (edges rounded - how to tell that it is enlargement)

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heart, hypertrophic cardiomyopathy, left wall and interventricular wall thicker - lumen non-existent

MD Sample taken from a dog who had a limb amputated due to a bony growth 1 mo prior.

liver, osteosarcoma, metastatic (multiple nodulues, irregularly round, 2mm-3cm, hard like bone, in capsule throughout parenchyma)

MD sample taken from patient who had a limb amputated 1 mo prior due to bony mass

liver, osteosarcoma, metastatic, x section showing tan spots through parenchyma

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Head Holoprosencephaly, cyclopia (one eye) arhinia (no nose) and cheiloschisis (split upper lip) (sheep exposed by day 14 to V. californicum with alkaloid --> cn cause holoprosencephaly)

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Head, holoprosencephaly, cyclopia, arhinia, cheiloschisis upper, umbilical hernia

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head, craniopegas

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head, brachygnathia, can't suckle poor doer (maloclusion of incisors, no negative pressure)

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head, brachygnathia, can't suckle poor doer

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whole body, chondrodysplastic dwarfism,domed head, laterally placed ears, pushed in nose, protruding tongue, short rotated legs, short vertebral column (defect in cartilage development)

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whole body, chondrodysplastic dwarfism,domed head, laterally placed ears, pushed in nose, protruding tongue, short rotated legs, short vertebral column, umbilical hernia

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Humerus, osteopetrosis, triangular wedges of bone that extend from physis to metaphysis, no marrow cavity due to osteoclast dysfunction, thin metaphysis, wide physis (retain bone in metaphysis, autosomal recessive in Angus calves due to inbreeding or line breeding)

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vertebral column, kyphosis

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vertebral column, scoliosis

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head, palatoschisis, died from starvation or aspiration pneumonia (can occur in hard or soft palate or both)

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head, cheiloschisis, triangular defect in lip extended up to nostril died due to inability to suckle

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Heart, high ventricular septal defect 1cm x 1.5 cm (sometimes incidental finding)

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head, hydranencephaly, incomplete epyndymal lining, little bit of cerebellum left, pretty hard to see

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Pluck, specifically heart, patent ductos arteriosis (pink spot on exam see open or something poked through) (open from pulmonary artery to aorta)

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Pluck, specifically heart, patent ductos arteriosis (pink spot on exam see open or something poked through)

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Brain, hydrocephalus, dilated lateral ventricles, thinner cortex, doming of skull if occurs before sutures due to pressure (tissue is there, normal epyndmal cell, lateral ventricles dilated, pressure can cause atrophy or necrosis, say how dilated)

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brain, hydrocephalus

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brain, cerebellar coning (pressure pushes brain out of skull)

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brain, cerebellar hypoplasia, say what size, how small say if cerebrum looks normal (definitive cause not known, can be random mutation, sheep border disease, cattle bvd, cats panleukopenia, pigs classicle swine fever)
causes of hydrocephaly
BVD - cattle
causes of hydranencephaly
in cattle, sheep and swine
BVD and akbane virus in cattle
Rif vallye fever and Cache Vallye virus in Sheep
Incidental in swine

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Hepatic lipidosis, diffuse pale, yellow, fragile, greasy, negative energy balance overwhelms hepatocytes

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Hepatic lipidosis, diffuse pale, yellow, fragile, greasy, negative energy balance overwhelms hepatocytes

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bone marrow, serous atrophy of fat - 50% of bone marrow made of adipose tissue, if starving - try to utilize ipid, should be white, if yellow, watery, serous - atrophy

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Intestine, granulomatous enteritis, diffuse metabolic disease causes malabsorption. Johne's disease, not hyperplasia, caused by macrophages causing inflammation

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Kidney, fibrosis, diffuse (End-stage kidney) renal failure, kidney shrunken, decreased GFR increases phosphourus, stimulates hyperplasia

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Mandible, fibrous osteodystrophy - replace bone with fibrous connective tissue

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Blood vessels and lung, calcification - metastatic

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Beak, rickets - osteomalasia in growing animal, disease due to decrease of vitamin D causes imbalance of calcium and phosphorous leading to mineralization, beak is soft

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long bone, rickets, soft

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brain, pituitary adenoma, neoplasm, often causes metabolic disease because of continuous pressure on hypothalamus which is the center for controlling body apperance, appetitie, hair coat, --> adenoma causes long hair coat, high fever w/o infectious disease, increased appetite

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Kidney, hemoglobin nephropathy, (excess Cu stored in liver, causes necrosis of the liver, so liver releases Cu into circulation which lyses RBC which causes increased hemoglobin in kidney which looks like black streaks in tubules and gives dark red urine.)

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