Glossary of Core Concepts in Pharmacology Ch 30

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acute gouty arthritis
uric acid crystals quickly accumulate in the joints of the big toes, heels, ankles, wrists, fingers, knees, or elbows, resulting in red, swollen, or inflamed tissue
antispasmodic drugs
medications that relieve symptoms of abnormal muscle tension and muscle spasticity
proteins called rheumatoid factors released by B lymphocytes

these tear down the body's own tissue
family of drugs that block bone resorption by inhibiting osteoclast activity
bone depostion
process of depositing mineral components into bone

the opposite of bone resorption
bone resorption
process of bone demineralization

breaks down bone into mineral components
intermediate form of Vitamin D
calcitonin therapy
treatment typically administered to women who cannot take estrogen or biphosphonate therapy

also for clients with Paget's disease
substance that is transformed in the kidneys during the second step of the conversion of Vitamin D to its active form
inactive form of Vitamin D
muscle spasm characterized by abnormal tension starting in one area of the body and progressing to other areas
estrogen replacement therapy (ERT)
course of treatment involving administration of reproductive hormones to postmenopausal women
metabolic disorder characterized by accumulation of uric acid in the bloodstream or joint cavities
disorder characterized by degeneration of joints such as the fingers, spine, hips, and knees
characterized by softening of bones w/o alteration of basic bone structure

rickets in children
condition where bones become brittle and susceptible to fracture
Paget's disease
disorder characterized by weak, enlarged, and abnormal bones
rheumatoid arthritis
systemic autoimmune disorder characterized by inflammation of multiple joints
selective estrogen receptor modulators (SERMs)
drugs that directly produce an action similar to estrogen in body tissues

used for treatment of osteoporosis in post-menopausal women
inability of opposing muscle groups to move in a coordinated manner
disorder characterized by prolonged muscle spasms, cramps, and twitches

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