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Glossary of Contaminants (CNTM)

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How do contaminant molds develop into infections?
They are opportunistic; usually 2ndary to another disease in immunocompromised
-due to neutropenia
-due to bad hygiene
How do we seperate the contaminant molds?
Based on microscopic morphology
What are the 5 groups of contaminant molds?
1. Aseptate hyphae (zygomyc)
2. Septate w/ conidiophore ending in a vesicle
3. Septate w/ conidiophore branching into Penicillus
4. Septate w/ conidia in clusters
5. Septate dematiceous
What are the molds that are aseptate?
Zygomycetes
-Rhizopus
-Mucor
-Absidia
What mold totally resembles zygomcetes but is not?
Syncephalastrum

WHAT IS IT?
Zygomycetes

WHAT IS IT?
aspergilloma

WHAT IS IT?
Aspergillus niger

WHAT IS IT?
Aspergillus fumigatus

WHAT IS IT?
Aspergillus fumigatus

WHAT IS IT?
Syncephalastrum

WHAT IS IT?
Paecilomyces vs. penicillium

WHAT IS IT?
Penicillium

WHAT IS IT?
paecilomyces

WHAT IS IT?
penicillium growth - slightly greenish

WHAT IS IT?
scopulariopsis

WHAT IS IT?
scopulariopsis

WHAT IS IT?
acremonium

WHAT IS IT?
acremonium

WHAT IS IT?
fusarium

WHAT IS IT?
fusarium

WHAT IS IT?
fusarium

WHAT IS IT?
Sepedonium

WHAT IS IT?
Chrysosporium

WHAT IS IT?
chrysosporium

WHAT IS IT?
Gliocladium

WHAT IS IT?
Gliocladium

WHAT IS IT?
Alternaria

WHAT IS IT?
Alternaria

WHAT IS IT?
Alternaria

WHAT IS IT?
curvularia

WHAT IS IT?
curvularia

WHAT IS IT?
drechslera

WHAT IS IT?
cladosporium

WHAT IS IT?
nigrospora

WHAT IS IT?
nigrospora

WHAT IS IT?
ulocladium

WHAT IS IT?
ulocladium

WHAT IS IT?
paecilomyces
What are the 2 molds with Septate hyphae ending in a vesicle?
1. Aspergillus
2. Syncephalastrum
What are the 4 species of Aspergillus we know of?
1. A. niger
2. A. fumigatus
3. A. flavus
4. A. glaucus
Which species of aspergillus is most likely to cause a serious systemic infection?
Aspergillus fumigatus
What are 6 diseases caused by aspergillus?
1. aspergilloma
2. Pulmonary spergillosis
3. Disseminated aspergillosis
4. Otitis externa
5. Keratitis
6. Alergic bronchopulmonary disease
What's another name for allergic bronchopulmonary disease?
Farmer's lung
What are the structures in aspergillus?
-Septate hyphae
-Conidiophore, terminates in a vesicle
-Phialides -> phialoconidia in chains
What are the structures in Syncephalastrum?
-Aseptate hyphae
-Sporangiophore, terminates in a vesicle
-Sporangiospores in chains come off vesicle
-Mesosporangia contains the chains of spores
What is common to both penicillium and paecilomyces?
Fingerlike spreading of phialides bearing phialoconidia
What is different between penicillium/paecilomyces?
-Elongated phialides in paecilomyces.
-ROUND phialoconidia in penicillium.
What species of penicillium is commonly seen in labs?
Penicillium marneffei
What colonial colors are:
-Penicillium
-Paecilomyces
Penicillium = white -> green
Paecilomycs = white -> tanner
What 5 molds have aseptate hyphae w/ conidia clustered?
1. Acremonium
2. Fusarium
3. Sepedonium
4. Chysosporium
5. Gliocladium
What does sepedonium resemble?
H. capsulatum (budding conidia)
What are characteriscts of Chyrsosporium?
Clavate, aseptate hyphae, intercalcary
What are the 6 demataceous fungi with septate hyphae?
CADCUN
Curvularia, alternaria, drechslera, cladosporium, ulocladium, nigrospora.
At maturity what colors are:
A. niger
A. fumigatus
A. flavus
A. glaucus
Niger = black
Fumigatus/flavus = dark green
Glaucus = yellow-brown
Which aspergillus has unique conidiophore, and what is it?
Aspergillus flavus; rough, echinulate conidiophore
which aspergillus species have double phialides? How are they arranged around ves?
Niger/flavus; cover entire vesicle and radiate OUT.
What type of vesicles does a. fumigatus have?
Single; cover upper 1/3 to 2/3 of vesicle and stick UP.
What type of vesicles does a. glaucus have?
Single; loosely arranged and radiate out.
Which aspergillus has cleistotheicia?
A. glaucus.

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