Cardiomyopathy Lecture
Terms
undefined, object
copy deck
- TRUE/FALSE - Cardiomyopathy, "heart muscle disease" does not include heart failure secondary to known etiology.
- True - Heart disorder in which the structural abnormality is limited to the myocardium.
- What are the 3 subtypes of Cardiomyopathy? Which is most common?
- Dilated (most common); Hypertrophic; Restrictive
- Certain cases of Dilated Cardiomyopathy have been shown to be caused by what inherited genetic abnormalities?
- X linked dystrophin genen (muscular dystrophy)
- Since progressive CHF is refractory to therapy, what is the definitive treatment for dilated cardiomyopathy?
- cardiac transplantation
- What are the 4 features that characterize dilated cardiomyopathy? Treatment?
- progressive cardiac hypertrophy, KEY dilation and contractile (systolic) dysfunction, progressive CHF sometimes from EtOH abuse. Treatment can be ACE Inhibitors but with time heart transplantation.
- What are the 3 features that characterize Hypertrophic cardiomyopathy? Treatment?
- disorganized myocardial hypertrophy (often only in the ventricular septum), abnormal diastolic filling, and (in many cases) intermittent ventricular outflow obstruction. Beta blockers are the standard treatment.
- 50% of hypertrophic cardiomyopathy is inherited in what pattern?
- Autosomal Dominant (often Beta-myosin heavy chain); Cause of young athlete death during exertion!
- What type of physical exam finding will you probably find with hypertrophic cardiomyopathy?
- harsh systolic ejection murmur
- What characterizes restrictive cardiomyopathy?
- Primary decrease in ventricular compliance (stiffness) resulting in impaired ventricular filling during diastole
- With many subtypes of restrictive cardiomyopathy, name 3 possible etiologies?
- Amyloidosis (Congo Red Stain); Hemochromatosis (Fe); Sarcoidosis
- Name the 2 uncommon associated conditions with restrictive cardiomyopathy.
- endomyocardial fibrosis; endocardial fibroelastosis
- How do restrictive cardiomyopathy and constrictive pericarditis differ in treatment?
- pericardial disease is amenable to surgical treatment.