Breast Pathology-:- Flash cards by cueFlash

cueFlash > Decks > Breast Pathology

Glossary of Breast Pathology

inflammatory conditions of breast: acute mastitis, granulomatous mastitis, mammary duct extasia, fat necrosis

acute mastitis: inflammatory condition, breast feeding, s. auereus, needs antibiotics

granulomatous mastititis: inflammatory conditon
foreign material, MTB, sarcoid,
may simulate carcinoma

mammary duct extasia: inflammatory condtion
dilated large and intmediate ducts filled with histiocytes, surrounded by fibrosis and inflmaation
subareolar

fat necrosis: inflammatory condition
necrosis of fat with inflammation, fibrosis and microcalcification
mass formation simulates carcinoma
trauma, ruptrues cysts

benign proliferative breast disease: benign proliferative breast disease
fibrcytic changes
ductal hyperplasia
radial scar

fibrocytic changes: benign proliferative breast disease
not a disease, physiologi phen
very common, simulate carc clin
dilation, apocrine metablasia, fibrosis, sclerosing sdenosis
RISK FOR CARCNOMA DETERMINED BY PRESENCE OF DUCTAL HYPERPLASIA, ESP ATYPICAL

ductal hyperplasia: benign proliferative breast disease
often accompanies fibrocytic change
increased epi cells in ducts
atypical is increased risk of breast carcinoma

fibroadenoma: benign neoplasm
common, enlarge during preg, regress with age
presents as mass
elongated ducts, smooth round contour, fibromyxoid cells

intraductal papilloma: benign
50yo
large ducts subareolar mass, nipple discharge
small ducts in young
papillary arch
spiculated

nipple papilloma: benign neoplasm
4-5th decades
ducts within nipple, discharge or erosion, simulate paget's disease
papillary arch

Ductal CIS: malignant neoplastic ductal type cells in BM in ducts and lobules
unifocal
invasive carc risk increased in ipsilateral breast
variable hist and cytologic atypia
comedocarcinoma

Lobular CIS: malignant neoplastic lobular type cells in BM
multifocal, bilateral
increased risk of carcinoma in both breasts

Paget's disease: CIS with tumor cells in epithelium of nipple
nipple with ulceration or eczema like change
associated with underlying carcinoma

Invasive Carcinoma of Breast: malignant epithelial neoplasm with stromal invasion by tumor, no longer confined to BM,
most common malignancy in women, 2nd most common cancer death in women
BRCA genes, hormone, radiation,
invasive ductal is vast majority, presents as mass, arranged in cords nests, invasive lobular, no clinical mass, lack of desmoplasia, diffuse growth pattern, single file cells
inflammatory , not distinct, erythemtous dermal changes, die within 2 yrs

phylloides tumor: leaf like, presents as mass, hypercellularity, overgrowth, bland ductal elements

male breast pathology: gynecomastia: increase estrogenic activity, decrease in androgenic activity or both,
cancer 1% of all breast cancer is male, nipple discharge is BAD

You must Login or Register to add cards