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Glossary of Block 2 PATH Exam -- Myocardial Disease Lecture

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Characteristics of Dilated Cardiomyopathy
Increased LV size
Increased LV filling pressure
N or Decreased LV compliance
Decreased SV, Ejection Fraction, and CO

NON-specific microscopic changes
Characteristics of Hypertrophic Cardiomyopathy
N or Decrased LV size
N or Increased LV filling pressure
Decreased LV compliance
Increased SV and Ejection Fraction
NORMAL CO

Distinctive microscopic changes: whorling, branching
Common, GENETICALLY INHERITED disorder
Beta-blockers, Calcium inhibitors occasionally effective
Characteristics of Restrictive Cardiomyopathy
N LV size
Increased LV filling pressure
Decreased LV compliance
Decreased SV, Ejection Fraction, and CO

Most cases are specific, rarely idiopathic (mainly in kids)
AMYLOID
No effective treatment
Characteristics of Obliterative Cardiomyopathy
SUBTYPE OF RESTRICTIVE
Decreased LV size
Increased LV filling pressure
Decreased LV compliance
Decreased SV, Ejection Fraction, and CO
No effective treatment
Endomyocardial Fibrosis
Subtropical, esp. in Africa
Children and young adults
May be end stage of hypereosinophilic syndrome
Endocardial Fibroelastosis
LV > LA > RV > RA
Common 0 - 2 years
Endocardium is 10X normal thickness!!!
Types of inflammation in types of myocarditis
VIRAL -- diffuse, mononuclear with edema and necrosis
BACTERIAL -- pathcy, acute, with microabscesses
AUTO-I/ALLERGIC -- diffuse, mononuclear, without necrosis
Types of Acute Pericarditis
SEROUS -- uremia, auto-i disease or uknown cause; rarely significant
FIBRINOUS -- most common; "bread and butter"; MI/radiation; adhesions
SUPPURATIVE -- invariably infectious; pts. are severely ill; scarring often
HEMORRHAGIC -- caused by tumor or Tb; scarring inevitable
CASEOUS -- necrosis WITHIN sac, Tb unless proven otherwise (chronic)
Sign of Constrictive Pericarditis
Small, quiet heart with reduced output and pulse pressure
Myxoma
Most common cardiac tumor
90% ATRIAL
L:R ratio is 4:1
BENIGN
May fragment or embolize

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