Glossary of Antimicrobial Drugs 2
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- 1. What is an antibiotic?
- Antimicrobial drugs produced by microorganisms
- 1. What is a synthetic drug?
- Antimicrobial drugs synthesized in the lab.
-Antibacterial synthetic drugs
-Antifungal synthetic drugs
- 1. List the five major ways by which an antibiotic or antimicrobial synthetic drug work?
- a. inhibition of cell wall synthesis
b. inhibition of protein synthesis
c. injury to plasma membrane
d. inhibition of nucleic acid synthesis
e. inhibition of synthesis of essential metabolites
- 1. What is selective toxicity? What group of antibiotics have the best selective toxicity? Why?
- 1. Are the sulfa drugs selectively toxic? Why or why not?
- 1. Know the action of each of the following: chloramphenical, streptomycin, erythromycin, tetracyclines.
- 1. List three drugs that stop the replication of Mycobacterium tuberculosis.
- 1. Why are there so many penicillins on the market today?
- 1. What does the 'R' group of penicillin do? How does it affect the activity of the penicillin?
- 1. Why is it so hard to find antiviral drugs? Antifungal drugs?
- 1. Why are the polyene antibiotics antifungal and not antibacterial?
- 1. How does AZT work?
- 1. List four ways bacteria become resistant to antibiotics.
- 1. Why can bacteria become resistant to antibiotics and not chemical disinfectants?
- 1. Do antibiotics do anything to viruses? Why or why not?
- 1. What does 'broad spectrum' mean? 'Narrow spectrum'?
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